GPR37

Gene Symbol GPR37
Entrez Gene 2861
Alt Symbol EDNRBL, PAELR, hET(B)R-LP
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 37 (endothelin receptor type B-like)
Other Description ETBR-LP-1|G-protein coupled receptor 37|Parkin-associated endothelin receptor-like receptor|endothelin B receptor-like protein 1|probable G-protein coupled receptor 37|prosaposin receptor GPR37
Swissprots A4D0Y6 Q8TD39 O14768 O15354 O00348
Accessions AAD08853 CAA73080 EAL24325 EAW83613 O15354 AF017262 AAB70008 AF502281 AAM18625 BC040007 AAH40007 DB475687 DB495592 DB517451 JF432421 ADZ15638 NM_005302 NP_005293
Function Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade. {ECO:0000269|PubMed:11439185, ECO:0000269|PubMed:23690594, ECO:0000269|PubMed:9526070}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17059562}; Multi-pass membrane protein {ECO:0000269|PubMed:17059562}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:17059562}; Multi-pass membrane protein {ECO:0000269|PubMed:17059562}.
Tissue Specificity Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ). {ECO:0000269|PubMed:9526070}.

Pael-R (G-6) - sc-390110 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pael-R (G-6): sc-390110. Western blot analysis of Pael-R expression in T98G whole cell lysate.

Pael-R (K-20) - sc-27549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pael-R (K-20): sc-27549. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Pael-R (A-20) - sc-27548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pael-R (A-20): sc-27548. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Pael-R (H-250) - sc-292396 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-GPCR GPR37 antibody - ab136958 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GPCR GPR37 antibody (ab136958) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-GPCR GPR37 antibody - ab133807 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GPCR GPR37 antibody (ab133807) at 1 µg/ml + Human fetal heart lysate at 10 µg

Anti-GPCR GPR37 antibody - ab115902 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115902, at 3 µg/ml, staining GPCR GPR37 in Formalin-fixed, Paraffin-embedded Human brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-GPCR GPR37 antibody [EPR10728] - ab166614 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10728
Anti-GPCR GPR37 antibody [EPR10728] (ab166614) at 1/1000 dilution + fetal brain lysate at 10 µg/mlSecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-GPCR GPR37 antibody - N-terminal - ab188928 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of Human brain (neuron and glia) tissue labeling GPCR GPR37 using ab188928 at 1 µg/ml.

Anti-PAEL Receptor / GPR37 Antibody - LS-C74025 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PAEL Receptor / GPR37 Antibody (aa211-260) - LS-C291470 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PAEL Receptor / GPR37 Antibody (aa199-248) - LS-C292026 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PAEL Receptor / GPR37 Antibody (aa468-517) - LS-C151730 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PAEL Receptor / GPR37 antibody Western Blot of Fetal Heart.

Anti-PAEL Receptor / GPR37 Antibody (N-Terminus) IHC-plus™ - LS-A127 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR37 antibody LS-A127 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PAEL Receptor / GPR37 Antibody (aa217-246) - LS-C99201 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-PAEL Receptor / GPR37 Antibody (N-Terminus) IHC-plus™ - LS-A4564 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR37 antibody LS-A4564 IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PAEL Receptor / GPR37 Antibody (aa97-126) - LS-C99200 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-PAEL Receptor / GPR37 Antibody (N-Terminus) IHC-plus™ - LS-A129 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PAEL Receptor / GPR37 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PAEL Receptor / GPR37 Antibody (N-Terminus) IHC-plus™ - LS-A131 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR37 antibody LS-A131 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR37 Antibody (436923) - MAB4450 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 436923
A172 human glioblastoma cell line was stained with Mouse Anti-Human GPR37 Monoclonal Antibody (Catalog # MAB4450, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.

GPR37 Antibody - NLS129 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR37 Antibody [NLS129] - Anti-PAEL Receptor / GPR37 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR37 Antibody - NLS131 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR37 Antibody [NLS131] - Anti-PAEL Receptor / GPR37 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR37 Antibody - NBP1-39602 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR37 Antibody [NBP1-39602] - Analysis of anti-GPR37 antibody with human brain at concentration 20 ug/ml.

GPR37 Antibody - NBP1-02361 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR37 Antibody [NBP1-02361] - Staining of human brain, cortex. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.

GPR37 Polyclonal Antibody - bs-13534R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-GPCR GPR37 Polyclonal Antibody, Unconjugated (bs-13534R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
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