GPR37

Gene Symbol GPR37
Entrez Gene 2861
Alt Symbol EDNRBL, PAELR, hET(B)R-LP
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 37 (endothelin receptor type B-like)
Other Description ETBR-LP-1|G-protein coupled receptor 37|Parkin-associated endothelin receptor-like receptor|endothelin B receptor-like protein 1|probable G-protein coupled receptor 37|prosaposin receptor GPR37
Swissprots A4D0Y6 Q8TD39 O14768 O15354 O00348
Accessions AAD08853 CAA73080 EAL24325 EAW83613 O15354 AF017262 AAB70008 AF502281 AAM18625 BC040007 AAH40007 DB475687 DB495592 DB517451 JF432421 ADZ15638 NM_005302 NP_005293
Function Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade. {ECO:0000269|PubMed:11439185, ECO:0000269|PubMed:23690594, ECO:0000269|PubMed:9526070}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17059562}; Multi-pass membrane protein {ECO:0000269|PubMed:17059562}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:17059562}; Multi-pass membrane protein {ECO:0000269|PubMed:17059562}.
Tissue Specificity Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ). {ECO:0000269|PubMed:9526070}.

Pael-R CRISPR/Cas9 KO Plasmid (h) - sc-405223 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R HDR Plasmid (h) - sc-405223-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R Double Nickase Plasmid (h) - sc-405223-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R Double Nickase Plasmid (h2) - sc-405223-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R CRISPR Activation Plasmid (h) - sc-405223-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R CRISPR Activation Plasmid (h2) - sc-405223-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R Lentiviral Activation Particles (h) - sc-405223-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R Lentiviral Activation Particles (h2) - sc-405223-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pael-R siRNA (h) - sc-106350 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pael-R shRNA Plasmid (h) - sc-106350-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pael-R shRNA (h) Lentiviral Particles - sc-106350-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU137411 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9603 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9603 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04262 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04262

GPR37 siRNA (Human) - CRH1920 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR37 RNAi - H00002861-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GPR37 - MBS8206588 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Gpr37 (NM_005302.3) - SHH306818 from Creative biogene

Category siRNA
Species Reactivities Human

Human GPR37 siRNA - orb262422 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR37 shRNA Plasmid (Human) - CHH1920 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPR37 miRNA 3'UTR clone - MiUTR3H-05098 from Creative biogene

Species Reactivities Human
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