CDCP1

Gene Symbol CDCP1
Entrez Gene 64866
Alt Symbol CD318, SIMA135, TRASK
Species Human
Gene Type protein-coding
Description CUB domain containing protein 1
Other Description CUB domain-containing protein 1|membrane glycoprotein gp140|subtractive immunization M plus HEp3-associated 135 kDa protein|transmembrane and associated with src kinases
Swissprots Q9H8C2 Q49UB4 Q96QU7 Q6U9Y2 Q9H5V8 Q8WU91 Q9H676 Q6NT71
Accessions EAW64737 EAW64738 Q9H5V8 AF468010 AAO33397 AK023834 BAB14695 AK026187 BAB15388 AK026329 AK026622 BAB15511 AK314441 AY026461 AAK02058 AY167484 AAO34538 AY358779 AAQ89139 AY375452 AAR21289 BC021099 AAH21099 BC069254 AAH69254 BC148605 AAI48606 BC153169 AAI53170 CD367582 XM_011534024 XP_011532326 NM_022842 NP_073753 NM_178181 NP_835488
Function May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. {ECO:0000269|PubMed:11466621, ECO:0000269|PubMed:12799299, ECO:0000269|PubMed:15153610, ECO:0000269|PubMed:16007225, ECO:0000269|PubMed:16404722, ECO:0000269|PubMed:8647901}.
Subcellular Location Isoform 1: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Shedding may also lead to a soluble peptide.
Tissue Specificity Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells. {ECO:0000269|PubMed:11466621, ECO:0000269|PubMed:12660814, ECO:0000269|PubMed:15153610, ECO:0000269|PubMed:16007225}.

CDCP1-Over-expression-Lysate - LY10321a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CDCP1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDCP1 gene (Lane 2, Cat. #LY10321a).

CDCP1 293T Cell Transient Overexpression Lysate(Denatured) - H00064866-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CDCP1 overexpression lysate - LY406018 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CDCP1 293 Cell Lysate - 403789 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CDCP1 293 Cell Lysate - 402572 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

CDCP1 Overexpression Lysate (Denatured) - H00064866-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: CDCP1 transfected lysate (37.84 KDa) Lane 2: Non-transfected lysate.

CDCP1 Overexpression Lysate (Native) - NBL1-09023 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: CDCP1 Overexpression Lysate (Adult Normal) [NBL1-09023] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDCP1.

CDCP1 Over-expression Lysate Product - GWB-B2762D from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

CDCP1 Over-expression Lysate Product - GWB-9AACA2 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Rhesus CDCP1 HEK293 Cell Lysate (WB positive control) - 90296-C08HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Rhesus

Human CDCP1 / CD318 HEK293 Cell Lysate (WB positive control) - 13262-H05HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human CDCP1 Human Cells Transfected Lysate (positive control) (denatured) - orb174360 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

CDCP1 Overexpression Lysate (Native) - NBP2-04991 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CDCP1 Overexpression Lysate (Adult Normal) [NBP2-04991] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDCP1.

Panoply™ Human CDCP1 Knockdown Stable Cell Line - CSC-DC002827 from Creative biogene

Category Cell Line
Species Human
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