SNCB

Gene Symbol	SNCB
Entrez Gene	6620
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	synuclein, beta
Other Description	beta-synuclein
Swissprots	Q6IAX7 Q16143
Accessions	AAC80286 EAW85063 EAW85064 Q16143 AB209029 BAD92266 AK309135 BC002902 AAH02902 BM543516 BM967045 BT006627 AAP35273 CR457027 CAG33308 DQ892970 ABM83896 DQ896218 ABM87217 JF960950 AEQ54756 JF960951 AEQ54757 JF960952 AEQ54758 JF960953 AEQ54759 S69965 AAB30860 XM_006714914 XP_006714977 XM_006714915 XP_006714978 XM_006714916 XP_006714979 XM_011534640 XP_011532942 NM_001001502 NP_001001502 NM_003085 NP_003076
Function	Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53- dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Subcellular Location	Cytoplasm.
Tissue Specificity	Expressed predominantly in brain; concentrated in presynaptic nerve terminals.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNCB cDNA clone(NM_001001502.1) - CDFH018232 from Creative Biomart Species Human Accession NM_001001502.1

Human SNCB cDNA clone(NM_003085.3) - CDFH018233 from Creative Biomart Species Human Accession NM_003085.3

Human SNCB ORF clone(NM_001001502.1) - CDCL186254 from Creative Biomart Species Human Accession NM_001001502.1

Human SNCB ORF Clone(NM_003085.3) - CDCR284815 from Creative Biomart Species Human Accession NM_003085.3

Human SNCB ORF Clone(NM_003085.3) - CDCR284816 from Creative Biomart Species Human Accession NM_003085.3

Human SNCB ORF Clone(NM_003085.3) - CDCR284817 from Creative Biomart Species Human Accession NM_003085.3

Human SNCB ORF Clone(NM_001001502.1) - CDCR338284 from Creative Biomart Species Human Accession NM_001001502.1

Human SNCB ORF Clone(NM_001001502.1) - CDCR338285 from Creative Biomart Species Human Accession NM_001001502.1

Human SNCB ORF Clone(NM_001001502.1) - CDCR338286 from Creative Biomart Species Human Accession NM_001001502.1

human SNCB ORF clone - CDCH083960 from Creative Biomart Species Human Accession NM_001001502

human SNCB ORF clone - CDCH083961 from Creative Biomart Species Human Accession NM_001001502

Human SNCB ORF Clone(NM_003085.3) - CDCL176506 from Creative Biomart Species Human Accession NM_003085.3

Human SNCB Gene ORF cDNA clone in cloning vector - HG11386-M from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11386-CM from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, N-HA tag - HG11386-NY from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11386-M-F from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11386-ACR from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11386-ANR from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid - HG11386-UT from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, C-HA tag - HG11386-CY from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, C-His tag - HG11386-CH from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11386-ACG from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, N-His tag - HG11386-NH from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11386-NF from Sino Biological Species Human

Human SNCB Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11386-NM from Sino Biological Species Human

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