SNCB

Gene Symbol SNCB
Entrez Gene 6620
Alt Symbol -
Species Human
Gene Type protein-coding
Description synuclein, beta
Other Description beta-synuclein
Swissprots Q6IAX7 Q16143
Accessions AAC80286 EAW85063 EAW85064 Q16143 AB209029 BAD92266 AK309135 BC002902 AAH02902 BM543516 BM967045 BT006627 AAP35273 CR457027 CAG33308 DQ892970 ABM83896 DQ896218 ABM87217 JF960950 AEQ54756 JF960951 AEQ54757 JF960952 AEQ54758 JF960953 AEQ54759 S69965 AAB30860 XM_006714914 XP_006714977 XM_006714915 XP_006714978 XM_006714916 XP_006714979 XM_011534640 XP_011532942 NM_001001502 NP_001001502 NM_003085 NP_003076
Function Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53- dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Subcellular Location Cytoplasm.
Tissue Specificity Expressed predominantly in brain; concentrated in presynaptic nerve terminals.

β-synuclein siRNA (h) - sc-36594 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β-synuclein shRNA Plasmid (h) - sc-36594-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β-synuclein shRNA (h) Lentiviral Particles - sc-36594-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α/β-synuclein siRNA (h) - sc-43589 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α/β-synuclein shRNA Plasmid (h) - sc-43589-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α/β-synuclein shRNA (h) Lentiviral Particles - sc-43589-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU037291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19862 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19862 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SNCB siRNA (Human) - CRH4503 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNCB - MBS8202124 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SNCB (NM_003085.3) - SHH414016 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SNCB(NM_003085.3) - SHL021562 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SNCB(NM_001001502.1) - SHL021616 from Creative biogene

Category siRNA
Species Reactivities Human

SNCB shRNA Plasmid (Human) - CHH4503 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SNCB miRNA 3'UTR clone - MiUTR1H-09685 from Creative biogene

Species Reactivities Human

SNCB miRNA 3'UTR clone - MiUTR1H-09686 from Creative biogene

Species Reactivities Human
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