Gene Symbol | MYBBP1A |
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Entrez Gene | 10514 |
Alt Symbol | P160, PAP2 |
Species | Human |
Gene Type | protein-coding |
Description | MYB binding protein (P160) 1a |
Other Description | myb-binding protein 1A|p53-activated protein-2 |
Swissprots | Q9BW49 Q9BQG0 Q9UF99 Q9P0V5 Q86VM3 |
Accessions | EAW90435 EAW90436 EAW90437 Q9BQG0 AF147709 AAF33021 AK095205 AK293458 BAG56953 AK301622 BAG63107 AK303150 BAG64253 AK307948 AL133098 CAB61409 AL136595 CAB66530 AY093673 AAM44451 BC000641 AAH00641 BC050546 AAH50546 BF111023 CB243989 DC346952 EU832503 ACE87675 XM_011523616 XP_011521918 NM_001105538 NP_001099008 NM_014520 NP_055335 |
Function | May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. {ECO:0000250|UniProtKB:Q7TPV4}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12429849}. Nucleus {ECO:0000269|PubMed:12429849}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. Note=Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar. {ECO:0000250|UniProtKB:Q7TPV4}. |
Human MYBBP1A peptide - ab104957 from Abcam
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Human MYBBP1A protein fragment - ab153093 from Abcam
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MYBBP1A Antibody Blocking Peptide - LS-E6683 from LifeSpan Bioscience
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MYBBP1A Antibody Blocking Peptide - LS-E14101 from LifeSpan Bioscience
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MYBBP1A Antibody Blocking Peptide - LS-E13350 from LifeSpan Bioscience
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Recombinant Human MYBBP1A Protein - H00010514-Q01 from Novus Biologicals
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MYBBP1A-AntibodyN-term-Blocking-peptide - BP19507a from Abgent, a WuXi AppTec company
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MYBBP1A Protein Lysate (APL10716) - APL10716 from Aviva Systems Biology
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MYBBP1A Protein Lysate (APL10717) - APL10717 from Aviva Systems Biology
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MYBBP1A - H00010514-Q01-10 from Acris Antibodies
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MYBBP1A - H00010514-Q01-25 from Acris Antibodies
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MYBBP1A fusion protein - ag6008 from Proteintech Group
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MYBBP1A Recombinant Protein Antigen - NBP2-13630PEP from Novus Biologicals
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MYBBP1A Protein Lysate - orb333491 from Biorbyt
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MYBBP1A Peptide, Human - M34GP09963H from Creative Peptides
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MYBBP1A Protein Lysate - orb333492 from Biorbyt
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