Gene Symbol | MYBBP1A |
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Entrez Gene | 10514 |
Alt Symbol | P160, PAP2 |
Species | Human |
Gene Type | protein-coding |
Description | MYB binding protein (P160) 1a |
Other Description | myb-binding protein 1A|p53-activated protein-2 |
Swissprots | Q9BW49 Q9BQG0 Q9UF99 Q9P0V5 Q86VM3 |
Accessions | EAW90435 EAW90436 EAW90437 Q9BQG0 AF147709 AAF33021 AK095205 AK293458 BAG56953 AK301622 BAG63107 AK303150 BAG64253 AK307948 AL133098 CAB61409 AL136595 CAB66530 AY093673 AAM44451 BC000641 AAH00641 BC050546 AAH50546 BF111023 CB243989 DC346952 EU832503 ACE87675 XM_011523616 XP_011521918 NM_001105538 NP_001099008 NM_014520 NP_055335 |
Function | May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. {ECO:0000250|UniProtKB:Q7TPV4}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12429849}. Nucleus {ECO:0000269|PubMed:12429849}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. Note=Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar. {ECO:0000250|UniProtKB:Q7TPV4}. |
MYBBP1A (S-14) - sc-161122 from Santa Cruz Biotechnology
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Anti-MYBBP1A antibody - ab99361 from Abcam
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Anti-MYBBP1A antibody - ab54160 from Abcam
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Anti-MYBBP1A antibody - ab89121 from Abcam
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Anti-MYBBP1A antibody - ab93835 from Abcam
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Anti-MYBBP1A antibody - ab84718 from Abcam
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Anti-MYBBP1A antibody [EPR7204] - ab125026 from Abcam
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Anti-MYBBP1A Antibody (C-Terminus) - LS-C9148 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287, AP) - LS-C263777 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287, APC) - LS-C263778 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287, Biotin) - LS-C263780 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287, Azide-free, HRP) - LS-C263782 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287, FITC) - LS-C263781 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287, PE) - LS-C263783 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa1278-1328) - LS-C288137 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287) - LS-C323175 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa1125-1174) - LS-C80169 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (C-Terminus) - LS-C145970 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa1151-1200) - LS-C116069 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (Internal, clone EPR7204) - LS-C139022 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa258-287) - LS-C157986 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa1201-1250) - LS-C31486 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody - LS-C333317 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa450-500) - LS-C288138 from LifeSpan Bioscience
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Anti-MYBBP1A Antibody (aa450-500) - LS-C286548 from LifeSpan Bioscience
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