RNGTT

Gene Symbol	RNGTT
Entrez Gene	8732
Alt Symbol	CAP1A, HCE, HCE1, hCAP
Species	Human
Gene Type	protein-coding
Description	RNA guanylyltransferase and 5'-phosphatase
Other Description	HCAP1|mRNA-capping enzyme
Swissprots	O60351 Q5TCW8 O60942 Q8WUM8 E1P513 O43483 E1P514 O60257
Accessions	EAW48566 EAW48567 EAW48568 EAW48569 EAW48570 O60942 AB009022 BAA25894 AB009023 BAA25895 AB009024 BAA25896 AB012142 BAA25198 AB012143 BAA25199 AF025654 AAB91559 AI193199 AK295719 BAG58562 AK299777 BAG61660 AK312407 BAG35320 BC019954 AAH19954 BP256840 BP396964 BX537450 CAD97693 JF432295 ADZ15512 XM_011536219 XP_011534521 XR_942617 NM_001286426 NP_001273355 NM_001286428 NP_001273357 NM_003800 NP_003791
Function	Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. {ECO:0000269|PubMed:21636784, ECO:0000269|PubMed:9473487, ECO:0000269|PubMed:9512541}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Isoform 1 and isoform 4 (at a lesser extent) are expressed in cerebrum, cerebellum, thyroid, lung, heart, liver, kidney, spleen, large intestine, testis, skin and muscle.
Top Pathways	mRNA surveillance pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HCE full length protein - ab160166 from Abcam Category Protein Source Wheat germ Species Human

Human HCE full length protein - ab183246 from Abcam Category Protein Source E. coli Species Human

RNGTT / HCAP Antibody Blocking Peptide - LS-E17577 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RNGTT Recombinant Protein - H00008732-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RNGTT protein (His tag) - 80R-3938 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

RNGTT / HCE (1-597, His-tag) - AR51625PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

RNGTT / HCE (1-597, His-tag) - AR51625PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

RNGTT / HCE - H00008732-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RNGTT / HCE - H00008732-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RNGTT fusion protein - Ag3105 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RNGTT, GST-tagged - RNGTT-2349H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human mRNA-capping enzyme(RNGTT) - CSB-YP526449HU CSB-EP526449HU CSB-BP526449HU CSB-MP526449HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RNGTT, 1-597aa, Human, His tag, E.coli - ATGP2805 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

RNA Guanylyltransferase And 5'-Phosphatase (Recombinant) - abx073857 from Abbexa

RNGTT / HCE - TP302229 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RNGTT Recombinant Protein Antigen - NBP1-83281PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RNGTT-Antibody-C-term-Blocking-Peptide - BP6617b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RNGTT Peptide, Human - M34GP13448H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human RNGTT Protein - NBP2-51817 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 50 µg, 250 µg Source E.coli Species Human

RNA Guanylyltransferase And 5'-Phosphatase, Human Recombinant - 228-20768-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

RNGTT - PAT-82804-1 from Nordic BioSite Category Protein Species Human

RNGTT - PAT-82804-2 from Nordic BioSite Category Protein Species Human

mRNA-capping enzyme (A103R), Recombinant Protein - MBS1347381 from MyBioSource Category Protein Prices $1,090.00, $1,090.00, $1,320.00, $1,320.00, $1,715.00, $1,715.00, $2,180.00, $2,180.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

mRNA-capping enzyme (RNGTT), Recombinant Protein - MBS1039437 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,615.00, $1,615.00, $2,340.00, $2,340.00, $2,780.00, $2,780.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

RNA Guanylyltransferase And 5'-Phosphatase, Recombinant Protein - MBS140783 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

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