Gene Symbol | PNRC2 |
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Entrez Gene | 55629 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | proline-rich nuclear receptor coactivator 2 |
Other Description | - |
Swissprots | B4DU72 Q9NPJ4 |
Accessions | EAW95101 EAW95102 Q9NPJ4 AF151042 AAF36128 AF374386 AAK54613 AK000319 BAA91082 AK024774 AK300522 BAG62234 AK311305 BC001959 AAH01959 BC068475 BC078177 AAH78177 BC085018 AAH85018 DA043474 NM_017761 NP_060231 |
Function | Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure. {ECO:0000269|PubMed:11574675, ECO:0000269|PubMed:19150429}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19150429}. Cytoplasm, P-body {ECO:0000269|PubMed:19150429}. |
Tissue Specificity | Expressed in heart, lung, muscle and brain. {ECO:0000269|PubMed:11574675}. |
PNRC2 (C-14) - sc-160673 from Santa Cruz Biotechnology
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PNRC2 (N-13) - sc-160674 from Santa Cruz Biotechnology
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Anti-PNRC2 antibody - ab169934 from Abcam
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Anti-PNRC2 Antibody - LS-C332445 from LifeSpan Bioscience
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Anti-PNRC2 Antibody (N-Terminus) - LS-C135420 from LifeSpan Bioscience
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Anti-PNRC2 Antibody (aa71-120) - LS-C116661 from LifeSpan Bioscience
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PNRC2 Antibody - NBP1-86384 from Novus Biologicals
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PNRC2 Antibody - NBP1-79660 from Novus Biologicals
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Anti-PNRC2 antibody produced in rabbit - SAB2107238 from Sigma-Aldrich
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Anti-PNRC2 antibody produced in rabbit - HPA027820 from Sigma-Aldrich
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PNRC2 antibody - middle region (ARP57028_P050) - ARP57028_P050 from Aviva Systems Biology
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Pnrc2 antibody - 70R-9468 from Fitzgerald
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PNRC2 antibody - 70R-19385 from Fitzgerald
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PNRC2 antibody - 70R-3985 from Fitzgerald
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PNRC2 Polyclonal Antibody - A3244 from ABclonal
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PNRC2 antibody - orb155183 from Biorbyt
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PNRC2 Antibody - abx036107 from Abbexa
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PNRC2 Antibody - abx002323 from Abbexa
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PNRC2 antibody - 51050-1-AP from Acris Antibodies
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Anti-PNRC2, Polyclonal Antibody - 25-A3244 from ARP American Research Products
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PNRC2 antibody - STJ26220 from St John's Laboratory Ltd
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PNRC2 antibody - 51050-1-AP from Proteintech Group
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PNRC2 - A3244 from NeoScientific
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PNRC2 Antibody - E306504 from Enogene
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PNRC2 Antibody - GWB-MU643D from Genway Biotech
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