SERPINC1

Gene Symbol SERPINC1
Entrez Gene 462
Alt Symbol AT3, AT3D, ATIII, THPH7
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade C (antithrombin), member 1
Other Description antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
Swissprots Q13815 B2R6P0 Q9UC78 P78439 P78447 P01008 Q5TC78 Q7KZ97 Q7KZ43
Accessions AAA19930 AAA51793 AAA51794 AAA51795 AAA51796 AAB19468 AAB23132 AAB40025 AAK60337 AAZ38825 BAC21173 BAC21174 BAC21175 BAC21176 CAA25059 CAA25060 CAA26951 CAA26952 CAA48690 CAI45858 CBX54631 EAW90969 EAW90970 EAW90971 P01008 AF130100 AAG35525 AK312654 BAG35537 BC022309 AAH22309 D29832 BAA06212 H62671 H65301 H71210 R84868 XM_005245198 XP_005245255 NM_000488 NP_000479
Function Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. {ECO:0000269|PubMed:15853774}.
Subcellular Location Secreted, extracellular space.
Tissue Specificity Found in plasma.
Top Pathways Complement and coagulation cascades

ATIII (A-6) - sc-393867 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATIII (A-6): sc-393867. Western blot analysis of ATIII in human plasma (A) and ATIII expression in human liver tissue extract (B).

ATIII (C-18) - sc-32453 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ATIII (C-18): sc-32453. Western blot analysis of ATIII expression in Hep G2 (A), HeLa (B), NIH/3T3 (C) and c4 (D) whole cell lysates and rat liver (E) and mouse liver (F) tissue extracts.

ATIII (H-7) - sc-271987 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATIII (H-7): sc-271987. Western blot analysis of ATIII expression in non-transfected 293T: sc-117752 (A), mouse ATIII transfected 293T: sc-118611 (B) and Hep G2 (C) whole cell lysates.

ATIII (H-70) - sc-32887 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ATIII (H-70): sc-32887. Western blot analysis of ATIII expression in non-transfected: sc-117752 (A) and mouse ATIII transfected: sc-118611 (B) 293T whole cell lysates.

ATIII (D-20) - sc-32452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ATIII (D-20): sc-32452. Western blot analysis of ATIII in human plasma.

Anti-Antithrombin III antibody - ab8776 from Abcam

Prices $368.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-Antithrombin III antibody - ab124259 from Abcam

Prices $376.00
Sizes 50 µl
Host Sheep
Clonality Polyclonal
ab124259, at 5µg/ml, staining Antithrombin III in formalin-fixed, paraffin-embedded Human intestine vessels tissue.

Anti-Antithrombin III antibody - ab61376 from Abcam

Prices $370.00
Sizes 1 mg
Host Sheep
Clonality Polyclonal

Anti-Antithrombin III antibody - ab66234 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
All lanes : Anti-Antithrombin III antibody (ab66234) at 1 µg/mlLane 1 : Antithrombin III transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysate Lysates/proteins at 50 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-Antithrombin III antibody - ab19105 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-Antithrombin III antibody - ab30535 from Abcam

Host Goat
Clonality Polyclonal

Anti-Antithrombin III antibody [1 B7] (Biotin) - ab197585 from Abcam

Prices $368.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1 B7
Calibration curve of a Sandwich ELISA for TAT (Thrombin-Antithrombin) using ab191378 as capture antibody and ab197585 as detection antibody.

Anti-Antithrombin III antibody [8D5] - ab117851 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8D5
Flow cytometry image using ab117851 at a 1/100 dilution, staining HEK293T cells transfected with Antithrombin III (Red), or an empty vector control plasmid (Blue).

Anti-Antithrombin III antibody [BDI205] - ab20933 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone BDI205
IHC image of Antithrombin III staining in Human normal liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab20933, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Antithrombin III antibody [EP5372] - ab126598 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP5372
All lanes : Anti-Antithrombin III antibody [EP5372] (ab126598) at 1/1000 dilutionLane 1 : Human plasma lysateLane 2 : Human ovary cancer lysateLane 3 : Human testis lysateLane 4 : Fetal lung lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Antithrombin III antibody [EPR5371] - ab124808 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5371
All lanes : Anti-Antithrombin III antibody [EPR5371] (ab124808) at 1/1000 dilutionLane 1 : Human plasma lysateLane 2 : Human ovary cancer lysateLane 3 : Human testis lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-SERPINC1 / Antithrombin III Antibody (HRP) - LS-C193851 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody (Biotin) - LS-C193822 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody (HRP) - LS-C193852 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µg
Host Sheep
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody - LS-C193885 from LifeSpan Bioscience

Prices $295.00
Sizes 500 µg
Host Goat
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody - LS-C195057 from LifeSpan Bioscience

Prices $275.00
Sizes 10 ml
Host Goat
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody - LS-C193884 from LifeSpan Bioscience

Prices $265.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody - LS-C195058 from LifeSpan Bioscience

Prices $225.00
Sizes 10 ml
Host Goat
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody - LS-C195862 from LifeSpan Bioscience

Prices $205.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-SERPINC1 / Antithrombin III Antibody - LS-C196548 from LifeSpan Bioscience

Prices $245.00
Sizes 1 mg
Host Goat
Clonality Polyclonal
Search more