SERPINC1

Gene Symbol	SERPINC1
Entrez Gene	462
Alt Symbol	AT3, AT3D, ATIII, THPH7
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade C (antithrombin), member 1
Other Description	antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
Swissprots	Q13815 B2R6P0 Q9UC78 P78439 P78447 P01008 Q5TC78 Q7KZ97 Q7KZ43
Accessions	AAA19930 AAA51793 AAA51794 AAA51795 AAA51796 AAB19468 AAB23132 AAB40025 AAK60337 AAZ38825 BAC21173 BAC21174 BAC21175 BAC21176 CAA25059 CAA25060 CAA26951 CAA26952 CAA48690 CAI45858 CBX54631 EAW90969 EAW90970 EAW90971 P01008 AF130100 AAG35525 AK312654 BAG35537 BC022309 AAH22309 D29832 BAA06212 H62671 H65301 H71210 R84868 XM_005245198 XP_005245255 NM_000488 NP_000479
Function	Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. {ECO:0000269|PubMed:15853774}.
Subcellular Location	Secreted, extracellular space.
Tissue Specificity	Found in plasma.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SERPINC1 293T Cell Transient Overexpression Lysate(Denatured) - H00000462-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SERPINC1 293 Cell Lysate - 400245 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

Serpin C1/Antithrombin-III Overexpression Lysate (Denatured) - H00000462-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Serpin C1/Antithrombin-III Overexpression Lysate (Native) - NBL1-15852 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

SERPINC1 Over-expression Lysate Product - GWB-9917FD from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Cynomolgus SerpinC1 / AntithrombinIII / ATIII HEK293 Cell Lysate (WB positive control) - 90042-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human SerpinC1 / AntithrombinIII / ATIII HEK293 Cell Lysate (WB positive control) - 10142-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human Antithrombin III Deficient Plasma (EDTA) - D330104 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (EDTA) - D330105 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (EDTA) - D330106 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (Heparin) - D330107 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (Heparin) - D330108 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (Heparin) - D330109 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (Sodium Citrate) - D330101 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (Sodium Citrate) - D330102 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Plasma

Human Antithrombin III Deficient Plasma (Sodium Citrate) - D330103 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Antithrombin III Deficient Serum - D330110 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Serum

Human Antithrombin III Deficient Serum - D330111 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Serum

Human Antithrombin III Deficient Serum - D330112 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Serum

Human SerpinC1 Human Cells Transfected Lysate (positive control) (denatured) - orb173002 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Serpin C1/Antithrombin-III Overexpression Lysate (Denatured) - H00000462-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human SERPINC1 Knockdown Stable Cell Line - CSC-DC014056 from Creative biogene Category Cell Line Species Human

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