SERPINC1

Gene Symbol	SERPINC1
Entrez Gene	462
Alt Symbol	AT3, AT3D, ATIII, THPH7
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade C (antithrombin), member 1
Other Description	antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
Swissprots	Q13815 B2R6P0 Q9UC78 P78439 P78447 P01008 Q5TC78 Q7KZ97 Q7KZ43
Accessions	AAA19930 AAA51793 AAA51794 AAA51795 AAA51796 AAB19468 AAB23132 AAB40025 AAK60337 AAZ38825 BAC21173 BAC21174 BAC21175 BAC21176 CAA25059 CAA25060 CAA26951 CAA26952 CAA48690 CAI45858 CBX54631 EAW90969 EAW90970 EAW90971 P01008 AF130100 AAG35525 AK312654 BAG35537 BC022309 AAH22309 D29832 BAA06212 H62671 H65301 H71210 R84868 XM_005245198 XP_005245255 NM_000488 NP_000479
Function	Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. {ECO:0000269|PubMed:15853774}.
Subcellular Location	Secreted, extracellular space.
Tissue Specificity	Found in plasma.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active rat Antithrombin III full length protein - ab93317 from Abcam Category Protein Prices $450.00 Sizes 1 mg Source Native Species Rat

Cow Antithrombin III full length protein - ab167770 from Abcam Category Protein Prices $285.00 Sizes 1 mg Source Native Species Bovine

Human Antithrombin III full length protein - ab157920 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Antithrombin III full length protein - ab168883 from Abcam Category Protein Prices $285.00 Sizes 50 µg Source Native Species Human

Human Antithrombin III full length protein - ab95077 from Abcam Category Protein Prices $450.00 Sizes 1 ml Source Native Species Human

Human Antithrombin III full length protein - ab177732 from Abcam Category Protein Prices $301.00 Sizes 100 µg Source E. coli Species Human

Human Antithrombin III full length protein - ab91119 from Abcam Category Protein Prices $356.00 Sizes 100 µg Source Native Species Human

Human Antithrombin III full length protein - ab62542 from Abcam Category Protein Prices $290.00 Sizes 1 mg Source Native Species Human

Human Antithrombin III full length protein - ab77942 from Abcam Category Protein Prices $356.00 Sizes 1 mg Source Native Species Human

Mouse Antithrombin III full length protein - ab169055 from Abcam Category Protein Source Native Species Mouse

Mouse Antithrombin III full length protein - ab93233 from Abcam Category Protein Source Native Species Mouse

Rat Antithrombin III full length protein - ab167778 from Abcam Category Protein Source Native Species Rat

SERPINC1 / Antithrombin III Antibody Blocking Peptide - LS-E8409 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SERPINC1 / Antithrombin III Antibody Blocking Peptide - LS-E15231 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Serpin C1/Antithrombin-III Recombinant Protein - H00000462-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Serpin C1/Antithrombin-III Protein - P4952 from Novus Biologicals Category Protein Prices $669.00 Sizes 1 mg Species Human

SERPINC1-Antibody-C-term-Blocking-Peptide - BP6715b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Serpin C1/Antithrombin-III, CF - 1267-PI-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, His33-Lys464, with a C-terminal 10-His tag

Human Plasma Antithrombin III Protein (OPMA04237) - OPMA04237 from Aviva Systems Biology Category Protein Prices $130.00 Sizes 100 µg Species Human

Cynomolgus SerpinC1 protein (His Tag) - orb139648 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Human Cells

Human SerpinC1 His tag protein - orb83116 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Human Species Human

Human Plasma Antithrombin III protein - orb82116 from Biorbyt Category Protein Prices $238.00 Sizes 100 μg Source Sample obtained from Human Plasma. Species Human

Antithrombin III protein - 30-AA50 from Fitzgerald Category Protein Prices $595.00 Sizes 1 mg

Antithrombin III protein - 30C-CP3007U from Fitzgerald Category Protein Prices $275.00 Sizes 1 mg

SERPINC1 Blocking Peptide - 33R-4150 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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