USP3

Gene Symbol	USP3
Entrez Gene	9960
Alt Symbol	SIH003, UBP
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 3
Other Description	deubiquitinating enzyme 3|ubiquitin carboxyl-terminal hydrolase 3|ubiquitin thioesterase 3|ubiquitin thiolesterase 3|ubiquitin-specific-processing protease 3
Swissprots	B4DVU5 Q9Y6I4 F5H1A6 Q8WVD0
Accessions	EAW77651 Q9Y6I4 AF073344 AAD42992 AF077040 AAD27773 AI695842 AK022931 BAG51139 AK094444 AK300948 BAG62577 AK301236 BAG62807 AK301563 BAG63058 AK307810 AK309382 AK314223 AY461579 AAT37507 BC018113 AAH18113 BC065300 AAH65300 BC100029 AAI00030 BC107137 AAI07138 BC107138 AAI07139 BT007269 AAP35933 BX647760 DA557812 DQ891025 ABM81951 DQ894205 ABM85131 XM_006720789 XP_006720852 XM_006720790 XP_006720853 XM_006720791 XP_006720854 XM_011522265 XP_011520567 XM_011522266 XP_011520568 NM_001256702 NP_001243631 NM_006537 NP_006528 NR_046341 NR_046342
Function	Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. {ECO:0000269|PubMed:17980597}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17980597}. Note=Localizes preferentially with monoubiquitinated H2A to chromatin.
Tissue Specificity	Expressed in all tissues examined, with strongest expression in pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human USP3 peptide - ab23058 from Abcam Category Peptide Species Human

Human USP3 protein fragment - ab127142 from Abcam Category Protein Source E. coli Species Human

USP3 / UBP Antibody Blocking Peptide - LS-E11910 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP3 / UBP Antibody Blocking Peptide - LS-E11909 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP3 / UBP Antibody Blocking Peptide - LS-E6879 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP3 / UBP Antibody Blocking Peptide - LS-E6878 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human USP3 Protein - H00009960-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human USP3 Protein - H00009960-P02 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

USP3 Peptide - P0918 from Novus Biologicals Category Peptide Species Human

USP3 Peptide - P0917 from Novus Biologicals Category Peptide Species Human

USP3-Antibody-C-term-Blocking-Peptide - BP2132b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP3-Antibody-N-term-Blocking-Peptide - BP2132a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP3 blocking peptide - GTX24849-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

USP3 Blocking Peptide - 33R-3546 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

USP3 Blocking Peptide - 33R-3951 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

USP3 - H00009960-P02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

USP3 - H00009960-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

USP3 - H00009960-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

USP3 fusion protein - Ag14594 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

USP3 fusion protein - ag3085 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human USP3, His-tagged - USP3-3625H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 3(USP3) - CSB-YP896756HU CSB-EP896756HU CSB-BP896756HU CSB-MP896756HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

USP3 - TP309550 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

USP3-Antibody-C-term-Blocking-Peptide - BP2132c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP3 Peptide, Human - M34GP17172H from Creative Peptides Category Peptide Source Synthetic. Species Human

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