USP3

Gene Symbol USP3
Entrez Gene 9960
Alt Symbol SIH003, UBP
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 3
Other Description deubiquitinating enzyme 3|ubiquitin carboxyl-terminal hydrolase 3|ubiquitin thioesterase 3|ubiquitin thiolesterase 3|ubiquitin-specific-processing protease 3
Swissprots B4DVU5 Q9Y6I4 F5H1A6 Q8WVD0
Accessions EAW77651 Q9Y6I4 AF073344 AAD42992 AF077040 AAD27773 AI695842 AK022931 BAG51139 AK094444 AK300948 BAG62577 AK301236 BAG62807 AK301563 BAG63058 AK307810 AK309382 AK314223 AY461579 AAT37507 BC018113 AAH18113 BC065300 AAH65300 BC100029 AAI00030 BC107137 AAI07138 BC107138 AAI07139 BT007269 AAP35933 BX647760 DA557812 DQ891025 ABM81951 DQ894205 ABM85131 XM_006720789 XP_006720852 XM_006720790 XP_006720853 XM_006720791 XP_006720854 XM_011522265 XP_011520567 XM_011522266 XP_011520568 NM_001256702 NP_001243631 NM_006537 NP_006528 NR_046341 NR_046342
Function Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. {ECO:0000269|PubMed:17980597}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17980597}. Note=Localizes preferentially with monoubiquitinated H2A to chromatin.
Tissue Specificity Expressed in all tissues examined, with strongest expression in pancreas.

USP3 CRISPR/Cas9 KO Plasmid (h) - sc-404849 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 HDR Plasmid (h) - sc-404849-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 Double Nickase Plasmid (h) - sc-404849-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 Double Nickase Plasmid (h2) - sc-404849-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 CRISPR Activation Plasmid (h) - sc-404849-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 CRISPR Activation Plasmid (h2) - sc-404849-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 Lentiviral Activation Particles (h) - sc-404849-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 Lentiviral Activation Particles (h2) - sc-404849-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP3 siRNA (h) - sc-76835 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP3 shRNA Plasmid (h) - sc-76835-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP3 shRNA (h) Lentiviral Particles - sc-76835-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP3 RNAi - H00009960-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU011571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22578 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22578 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05975 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05975

USP3 siRNA (Human) - CRH6698 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USP3 - MBS8200342 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human USP3 (NM_006537.3) - SHH441456 from Creative biogene

Category siRNA
Species Reactivities Human

USP3 shRNA Plasmid (Human) - CHH6698 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

USP3 miRNA 3'UTR clone - MiUTR3H-07045 from Creative biogene

Species Reactivities Human
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