MMP17

Gene Symbol MMP17
Entrez Gene 4326
Alt Symbol MT4-MMP
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 17 (membrane-inserted)
Other Description MMP-17|MT-MMP 4|MT4MMP|MTMMP4|matrix metalloproteinase 17 (membrane-inserted)|matrix metalloproteinase-17|membrane-type matrix metalloproteinase 4|membrane-type-4 matrix metalloproteinase
Swissprots Q14850 Q9ULZ9
Accessions EAW98528 Q9ULZ9 AB021225 BAA82707 BC040507 AAH40507 BC045610 AAH45610 BX389435 CA489162 X89576 CAA61753 XM_011538355 XP_011536657 XM_011538356 XP_011536658 XM_011538357 XP_011536659 XR_944550 XR_944551 XR_944552 NM_016155 NP_057239
Function Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Subcellular Location Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix.
Tissue Specificity Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types.

MT-MMP-4 (C-18) - sc-8847 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MT-MMP-4 (C-18): sc-8847. Western blot analysis of MT-MMP-4 expression in NAMALWA whole cell lysate.

MT-MMP-4 (C-16) - sc-20909 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MT-MMP-4 (H-110) - sc-13972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MT-MMP-4 (H-110): sc-13972. Western blot analysis of MT-MMP-4 expression in MCF7 (A) and LNCaP (B) whole cell lysates.

Anti-MMP17 antibody - ab154485 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MMP17 antibody (ab154485) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-MMP17 antibody - ab39708 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP17 antibody (ab39708) at 1/1000 dilutionLane 1 : SW620 Cell LysateLane 2 : SW620 Cell LysateLysates/proteins at 20 µl per lane.

Anti-MMP17 antibody - ab115761 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Small Intestine (formalin-fixed, paraffin-embedded) stained with ab115761 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-MMP17 antibody - ab183156 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP17 antibody (ab183156) at 1/900 dilutionLane 1 : K562 cell lysateLane 2 : Human colon cancer tissue lysateLysates/proteins at 40 µg per lane.SecondaryGoat anti Rabbit IgG - H&L (HRP) at 1/5000 dilution

Anti-MMP17 antibody - ab28540 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP17 antibody - ab39026 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP17 antibody [EP1270Y] - ab51075 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1270Y
Anti-MMP17 antibody [EP1270Y] (ab51075) at 1/1000 dilution + Mouse brain lysate at 10 µgSecondaryGoat anti-Rabbit HRP labeled at 1/2000 dilution

Anti-MMP17 antibody - Aminoterminal end - ab39028 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Ab39028 staining human normal ovary. Staining is localised to plasma membrane.Left panel: with primary antibody at 4 ug/ml. Right panel: isotype control.Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 antigen retrieval buffer EDTA pH 9.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 minutes. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 minutes and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-MMP17 antibody - Carboxyterminal end - ab39027 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody - LS-C48501 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody - LS-C96161 from LifeSpan Bioscience

Prices $345.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody - LS-C130672 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (aa431-460, AP) - LS-C263290 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (aa431-460, APC) - LS-C263292 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (aa512-561) - LS-C151756 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MMP17 / MMP-17 antibody Western Blot of Jurkat.

Anti-MMP17 Antibody (aa431-460, Biotin) - LS-C263293 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (aa431-460, FITC) - LS-C263294 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (aa431-460, Azide-free, HRP) - LS-C263295 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (aa431-460, PE) - LS-C263296 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (Internal, AP) - LS-C279320 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (Internal, Biotin) - LS-C279322 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP17 Antibody (Internal, APC) - LS-C279321 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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