MMP17

Gene Symbol	MMP17
Entrez Gene	4326
Alt Symbol	MT4-MMP
Species	Human
Gene Type	protein-coding
Description	matrix metallopeptidase 17 (membrane-inserted)
Other Description	MMP-17|MT-MMP 4|MT4MMP|MTMMP4|matrix metalloproteinase 17 (membrane-inserted)|matrix metalloproteinase-17|membrane-type matrix metalloproteinase 4|membrane-type-4 matrix metalloproteinase
Swissprots	Q14850 Q9ULZ9
Accessions	EAW98528 Q9ULZ9 AB021225 BAA82707 BC040507 AAH40507 BC045610 AAH45610 BX389435 CA489162 X89576 CAA61753 XM_011538355 XP_011536657 XM_011538356 XP_011536658 XM_011538357 XP_011536659 XR_944550 XR_944551 XR_944552 NM_016155 NP_057239
Function	Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Subcellular Location	Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix.
Tissue Specificity	Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MT-MMP-4 CRISPR/Cas9 KO Plasmid (h) - sc-405757 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 HDR Plasmid (h) - sc-405757-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 Double Nickase Plasmid (h) - sc-405757-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 Double Nickase Plasmid (h2) - sc-405757-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 CRISPR Activation Plasmid (h) - sc-405757-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 CRISPR Activation Plasmid (h2) - sc-405757-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 Lentiviral Activation Particles (h) - sc-405757-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 Lentiviral Activation Particles (h2) - sc-405757-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 siRNA (h) - sc-35979 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MT-MMP-4 shRNA Plasmid (h) - sc-35979-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MT-MMP-4 shRNA (h) Lentiviral Particles - sc-35979-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MMP-17 RNAi - H00004326-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU150001 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14428 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14428 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05298 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05298

MMP17 siRNA (Human) - CRH2938 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MT-MMP-4 CRISPR/Cas9 KO Plasmid (h2) - sc-405757-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MT-MMP-4 HDR Plasmid (h2) - sc-405757-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human MMP17 (NM_016155.4) - SHH342948 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MMP17(NM_016155.4) - SHH193529 from Creative biogene Category siRNA Species Reactivities Human

Human MMP17 siRNA - orb263440 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MMP17 shRNA Plasmid (Human) - CHH2938 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MMP17 miRNA 3'UTR clone - MiUTR1H-06349 from Creative biogene Species Reactivities Human

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