Gene Symbol | MMP17 |
---|---|
Entrez Gene | 4326 |
Alt Symbol | MT4-MMP |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 17 (membrane-inserted) |
Other Description | MMP-17|MT-MMP 4|MT4MMP|MTMMP4|matrix metalloproteinase 17 (membrane-inserted)|matrix metalloproteinase-17|membrane-type matrix metalloproteinase 4|membrane-type-4 matrix metalloproteinase |
Swissprots | Q14850 Q9ULZ9 |
Accessions | EAW98528 Q9ULZ9 AB021225 BAA82707 BC040507 AAH40507 BC045610 AAH45610 BX389435 CA489162 X89576 CAA61753 XM_011538355 XP_011536657 XM_011538356 XP_011536658 XM_011538357 XP_011536659 XR_944550 XR_944551 XR_944552 NM_016155 NP_057239 |
Function | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
Subcellular Location | Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types. |
MMP17 peptide - ab41100 from Abcam
|
||||||||||
MMP17 peptide - ab43115 from Abcam
|
||||||||||
MMP17 peptide - ab46845 from Abcam
|
||||||||||
MMP17 Antibody Blocking Peptide - LS-E2871 from LifeSpan Bioscience
|
||||||||||
MMP17 Antibody Blocking Peptide - LS-E23541 from LifeSpan Bioscience
|
||||||||||
MMP17 Antibody Blocking Peptide - LS-E8127 from LifeSpan Bioscience
|
||||||||||
Recombinant Human MMP-17 Protein - P4928 from Novus Biologicals
|
||||||||||
MMP-17 Peptide - P1809 from Novus Biologicals
|
||||||||||
MMP17-Antibody-C-term-Blocking-peptide - BP13995b from Abgent, a WuXi AppTec company
|
||||||||||
MMP17-Antibody-Center-Blocking-Peptide - BP6201a from Abgent, a WuXi AppTec company
|
||||||||||
Recombinant Human MMP-17, CF - 7796-MP-010 from R&D Systems
|
||||||||||
MMP-17 - P4928 from Acris Antibodies
|
||||||||||
Recombinant Human MMP17, Catalytic Domain, His-tagged - MMP17-609H from Creative Biomart
|
||||||||||
Recombinant Matrix Metalloproteinase 17 (MMP17) - RPB846Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Matrix Metalloproteinase 17 (MMP17) - RPB846Hu01 from Cloud-clone
|
||||||||||
Recombinant Human Matrix metalloproteinase-17(MMP17) - CSB-YP891554HU CSB-EP891554HU CSB-BP891554HU CSB-MP891554HU from Cusabio
|
||||||||||
Recombinant Human MMP-17 Protein, CF - 7796-MP from R&D Systems
|
||||||||||
MMP17 Peptide - abx164622 from Abbexa
|
||||||||||
Recombinant Human MMP17 protein, His-tagged - MMP17-26H from Creative Biomart
|
||||||||||
Recombinant Human MMP17 protein - MMP17-27H from Creative Biomart
|
||||||||||
MMP17 Peptide, Human - M34GP09597H from Creative Peptides
|
||||||||||
Matrix Metalloproteinase 17 MT4 Catalytic Domain, Recombinant Protein - MBS635612 from MyBioSource
|
||||||||||
Matrix metalloproteinase-17 (MMP17), Recombinant Protein - MBS1446880 from MyBioSource
|
||||||||||
Recombinant Human MMP-17 Protein, CF - 7796-MP from Novus Biologicals
|
||||||||||
MMP17 peptide - orb72978 from Biorbyt
|