PORCN

Gene Symbol	PORCN
Entrez Gene	64840
Alt Symbol	DHOF, FODH, MG61, PORC, PPN
Species	Human
Gene Type	protein-coding
Description	porcupine homolog (Drosophila)
Other Description	probable protein-cysteine N-palmitoyltransferase porcupine|protein-cysteine N-palmitoyltransferase porcupine
Swissprots	Q9H236 B7ZAR3 Q9H234 Q14829 B2RBN8 Q9UJU7 Q9H237 Q9H235
Accessions	EAW50777 EAW50778 EAW50779 EAW50780 EAW50781 Q9H237 AF317058 AAG39628 AF317059 AAG39629 AF317060 AAG39630 AF317061 AAG39631 AK056340 AK057727 BAG51958 AK293347 BAG56863 AK314745 BAG37285 AK316378 BAH14749 AL538245 AL579208 BC019080 AAH19080 BM543485 BM545893 CN310467 DQ892632 ABM83558 DQ895869 ABM86795 HY002842 L08239 AAA74510 XM_005272635 XP_005272692 XM_005272636 XP_005272693 XM_005272637 XP_005272694 XM_006724544 XP_006724607 XM_006724545 XP_006724608 XM_006724546 XP_006724609 XM_006724547 XP_006724610 XM_011543948 XP_011542250 NM_001282167 NP_001269096 NM_022825 NP_073736 NM_203473 NP_982299 NM_203474 NP_982300 NM_203475 NP_982301 NM_203476
Function	protein-cysteine N-palmitoyltransferase that modulates the processing of Wnt proteins by mediating serine palmitoylation of Wnt family members. {ECO:0000269|PubMed:12034504, ECO:0000269|PubMed:20826466, ECO:0000269|PubMed:24292069}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity	Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis. Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis. Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung. {ECO:0000269|PubMed:12034504}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PORCN ELISA Kit (Custom ELISA) - LS-F19940 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.78-50 ng/ml

Mouse PORCN ELISA Kit (Custom ELISA) - LS-F19941 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.78-50 ng/ml

Probable protein-cysteine N-palmitoyltransferase porcupine, ELISA Kit - MBS288073 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.78 ng/mL -50.0 ng/mL.

PORCN - EKH4588 from Nordic BioSite Sensitivity 0.469ng/ml Range 0.78-50ng/ml

PORCN ELISA Kit (Human) (OKEH01732) - OKEH01732 from Aviva Systems Biology Category ELISA Kit Prices $450.00 Sizes 96 wells Sensitivity < 0.23 ng/mL Range 0.78 - 50 ng/mL

Human PORCN ELISA Kit - E030869 from Biobool Category ELISA Kit

Human Probable protein-cysteine N-palmitoyltransferase porcupine ELISA Kit - EK4639 from Signalway Antibody Category ELISA Kit Prices $659.00 Sizes 1x96t Range 0.78-50 ng/ml

Probable protein-cysteine N-palmitoyltransferase porcupine, ELISA Kit - MBS9428465 from MyBioSource Category ELISA Kit Prices $605.00 Sizes 96 tests Sensitivity Less than 0.23ng/mL Range 0.78-50 ng/mL

Human PORCN ELISA Kit (Sandwich ELISA) - LS-F33596 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.469 Range 0.78-50 ng/ml

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