PORCN

Gene Symbol PORCN
Entrez Gene 64840
Alt Symbol DHOF, FODH, MG61, PORC, PPN
Species Human
Gene Type protein-coding
Description porcupine homolog (Drosophila)
Other Description probable protein-cysteine N-palmitoyltransferase porcupine|protein-cysteine N-palmitoyltransferase porcupine
Swissprots Q9H236 B7ZAR3 Q9H234 Q14829 B2RBN8 Q9UJU7 Q9H237 Q9H235
Accessions EAW50777 EAW50778 EAW50779 EAW50780 EAW50781 Q9H237 AF317058 AAG39628 AF317059 AAG39629 AF317060 AAG39630 AF317061 AAG39631 AK056340 AK057727 BAG51958 AK293347 BAG56863 AK314745 BAG37285 AK316378 BAH14749 AL538245 AL579208 BC019080 AAH19080 BM543485 BM545893 CN310467 DQ892632 ABM83558 DQ895869 ABM86795 HY002842 L08239 AAA74510 XM_005272635 XP_005272692 XM_005272636 XP_005272693 XM_005272637 XP_005272694 XM_006724544 XP_006724607 XM_006724545 XP_006724608 XM_006724546 XP_006724609 XM_006724547 XP_006724610 XM_011543948 XP_011542250 NM_001282167 NP_001269096 NM_022825 NP_073736 NM_203473 NP_982299 NM_203474 NP_982300 NM_203475 NP_982301 NM_203476
Function protein-cysteine N-palmitoyltransferase that modulates the processing of Wnt proteins by mediating serine palmitoylation of Wnt family members. {ECO:0000269|PubMed:12034504, ECO:0000269|PubMed:20826466, ECO:0000269|PubMed:24292069}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis. Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis. Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung. {ECO:0000269|PubMed:12034504}.
Top Pathways Wnt signaling pathway

PORCN (G-15) - sc-139025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

PORCN (K-13) - sc-139026 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PORCN (K-13): sc-139026. Western blot analysis of PORCN expression in K-562 (A) and PC-12 (B) whole cell lysates.

Anti-PORCN antibody - ab105543 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PORCN antibody (ab105543) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-PORCN antibody - ab172664 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PORCN antibody (ab172664) at 1 µg/mlLane 1 : PORCN transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Rabbit IgG (H+L) HRP at 1/7500 dilutiondeveloped using the ECL technique

Anti-PORCN Antibody (aa130-179) - LS-C145383 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PORCN antibody LS-C145383 Western blot of Mouse Thymus lysate. Antibody concentration 1 ug/ml.

Anti-PORCN Antibody (aa38-87) - LS-C81450 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PORCN Antibody (aa224-239) - LS-C204273 from LifeSpan Bioscience

Prices $365.00
Sizes 1 ea
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of HeLa cells with PORCN antibody (10 ug/ml)

PORCN Antibody - NBP1-59677 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PORCN Antibody [NBP1-59677] - Sample Tissue: Human Hela Antibody Dilution: 1.0 ug/ml

PORCN Antibody - NBP2-13790 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PORCN Antibody [NBP2-13790] Staining of human stomach, lower shows distinct nuclear and cytoplasmic positivity in glandular cells.

Anti-PORCN antibody produced in rabbit - HPA049215 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PORCN:<B>Cat. No. HPA049215</B>: Immunohistochemical staining of human stomach, lower shows distinct nuclear and cytoplasmic positivity in glandular cells.

Anti-PORCN antibody produced in rabbit - SAB2101846 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PORCN: <B>Cat. No. SAB2101846</B>: Immunohistochemistry of PORCN in Mouse uterus tissue with PORCN antibody at 0.00333333333333333. U = Untreated equine cartilage. IL = IL-1β treated equine cartilage. T = TNF-α + IL-1β treated equine cartilage.

Anti-PORCN antibody produced in rabbit - SAB1412880 from Sigma-Aldrich

Prices $391.50
Sizes 100 µg
Host Rabbit
<B>Immunoblotting</B><BR/>Anti-PORCN:<B>Cat. No. SAB1412880</B>: Antibody concentration: 0.1–5 μg/mL. Immunofluorescence band of ~51 kDa using PORCN transfected 293T lysate.<BR/><B>Lane</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

PORCN antibody - N-terminal region (ARP49762_P050) - ARP49762_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Porcn antibody - 70R-8827 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PORCN antibody - 70R-6584 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PORCN antibody - H00064840-D01 from Acris Antibodies

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PORCN antibody - H00064840-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PORCN Antibody - GWB-MR636F from Genway Biotech

Prices $404.00
Sizes 50 µg
Clonality Polyclonal

Anti-PORCN (full length) polyclonal antibody - DPABH-10015 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-PORCN (aa 38-87) polyclonal antibody - DPABH-21827 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-PORCN monoclonal antibody - DCABH-201284 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

Anti-PORCN Antibody, clone 15G12.1 - MABS21 from EMD Millipore

Prices $259.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 15G12.1

Anti-PORCN Antibody (aa138-171) - LS-C356689 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PORCN Antibody at 1:2000 dilution Lane 1: mouse brain lysates Lane 2: mouse cerebellum lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

PORCN Antibody - middle region (OAAB19366) - OAAB19366 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PORCN antibody, N-term - GTX46000 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Search more