STOML2

Gene Symbol	STOML2
Entrez Gene	30968
Alt Symbol	HSPC108, SLP-2
Species	Human
Gene Type	protein-coding
Description	stomatin (EPB72)-like 2
Other Description	EPB72-like protein 2|paraprotein target 7|paratarg-7|stomatin-like 2|stomatin-like protein 2, mitochondrial
Swissprots	Q9P042 B4E1K7 Q9UJZ1 Q96FY2 D3DRN3 Q53G29 O60376
Accessions	AAC07983 CAG30023 CAH05402 EAW58394 EAW58395 EAW58396 Q9UJZ1 AA657517 AF161458 AAF29073 AF190167 AAF09142 AF282596 AAF91466 AK027405 BAB55091 AK130546 BAC85377 AK223102 BAD96822 AK225114 AK303883 BAG64819 AK307343 AK308552 AW273545 BC002442 AAH02442 BC003025 AAH03025 BC010152 AAH10152 BC014990 AAH14990 BQ935988 BU528995 BX400542 DQ892677 ABM83603 DQ895920 ABM86846 HY039403 HY367065 NM_001287031 NP_001273960 NM_001287032 NP_001273961 NM_001287033 NP_001273962 NM_013442 NP_038470
Function	Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation. {ECO
Subcellular Location	Mitochondrion inner membrane. Mitochondrion intermembrane space. Cell membrane; Peripheral membrane protein. Membrane raft; Peripheral membrane protein. Note=Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain. A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells. Also associates with the actin cytoskeleton and membrane rafts in activated T-cells.
Tissue Specificity	Ubiquitously expressed at low levels. Expressed in lymphoid tissues (at protein level). {ECO:0000269|PubMed:10713127, ECO:0000269|PubMed:11435687, ECO:0000269|PubMed:18641330}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

STOML2-Over-expression-Lysate - LY13601a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

STOML2 293T Cell Transient Overexpression Lysate(Denatured) - H00030968-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

STOML2 overexpression lysate - LY415542 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

STOML2 293 Cell Lysate - 407324 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SLP-2 Overexpression Lysate (Denatured) - H00030968-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

STOML2 (h): 293 Lysate - sc-172367 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

STOML2 Over-expression Lysate Product - GWB-E3AB36 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

SLP-2 Overexpression Lysate (Native) - NBP2-10338 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human STOML2 Knockdown Stable Cell Line - CSC-DC015329 from Creative biogene Category Cell Line Species Human

STOML2 KO Cell Lysate-HEK293T - CLKO-0917 from Creative biogene Category Cell Lysate

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