STOML2

Gene Symbol STOML2
Entrez Gene 30968
Alt Symbol HSPC108, SLP-2
Species Human
Gene Type protein-coding
Description stomatin (EPB72)-like 2
Other Description EPB72-like protein 2|paraprotein target 7|paratarg-7|stomatin-like 2|stomatin-like protein 2, mitochondrial
Swissprots Q9P042 B4E1K7 Q9UJZ1 Q96FY2 D3DRN3 Q53G29 O60376
Accessions AAC07983 CAG30023 CAH05402 EAW58394 EAW58395 EAW58396 Q9UJZ1 AA657517 AF161458 AAF29073 AF190167 AAF09142 AF282596 AAF91466 AK027405 BAB55091 AK130546 BAC85377 AK223102 BAD96822 AK225114 AK303883 BAG64819 AK307343 AK308552 AW273545 BC002442 AAH02442 BC003025 AAH03025 BC010152 AAH10152 BC014990 AAH14990 BQ935988 BU528995 BX400542 DQ892677 ABM83603 DQ895920 ABM86846 HY039403 HY367065 NM_001287031 NP_001273960 NM_001287032 NP_001273961 NM_001287033 NP_001273962 NM_013442 NP_038470
Function Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation. {ECO
Subcellular Location Mitochondrion inner membrane. Mitochondrion intermembrane space. Cell membrane; Peripheral membrane protein. Membrane raft; Peripheral membrane protein. Note=Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain. A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells. Also associates with the actin cytoskeleton and membrane rafts in activated T-cells.
Tissue Specificity Ubiquitously expressed at low levels. Expressed in lymphoid tissues (at protein level). {ECO:0000269|PubMed:10713127, ECO:0000269|PubMed:11435687, ECO:0000269|PubMed:18641330}.

STOML2 (C-3) - sc-376165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
STOML2 (C-3): sc-376165. Western blot analysis of STOML2 expression in HEL 92.1.7 (A), A-431 (B), TF-1 (C) and BT-20 (D) whole cell lysates.

STOML2 (H-180) - sc-98709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
STOML2 (H-180): sc-98709. Western blot analysis of STOML2 expression in BT-20 (A), HEL 92.1.7 (B), TF-1 (C) and A-431 (D) whole cell lysates.

STOML2 (V-19) - sc-83049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-STOML2 antibody - ab37531 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
All lanes : Anti-STOML2 antibody (ab37531) at 1/2000 dilutionLane 1 : Mouse liver tissue lysateLane 2 : Mouse hepatocytes cell lysateLysates/proteins at 25 µg per lane.SecondaryHRP-conjugated goat anti-chicken IgY polyclonal at 1/20000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-STOML2 antibody - ab157495 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STOML2 antibody (ab157495) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : K562 lysateLane 3 : A431 lysateLane 4 : 293T lysateLane 5 : HepG2 lysate

Anti-STOML2 antibody - ab89025 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-STOML2 antibody (ab89025) at 1 µg/ml + human placenta tissue lysate at 50 µg

Anti-STOML2 antibody - ab102051 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-STOML2 antibody (ab102051) at 1/500 dilution + Human kidney tissue lysate at 50 µgdeveloped using the ECL technique

Anti-STOML2 antibody - ab156373 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-STOML2 antibody (ab156373) at 1/100 dilution + HepG2 cell lysate at 35 µg

Anti-STOML2 antibody - ab117876 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-STOML2 antibody (ab117876) at 1 µg/ml + 721_B cell lysate at 10 µg

Anti-STOML2 Antibody (aa161-189, AP) - LS-C227096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (aa161-189, FITC) - LS-C227100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (aa161-189, APC) - LS-C227099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (aa161-189, Biotin) - LS-C227101 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (aa161-189, Azide-free, HRP) - LS-C227102 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (aa161-189, PE) - LS-C227103 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (aa161-189) - LS-C325465 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (C-Terminus) - LS-C145473 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
STOML2 antibody LS-C145473 Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.

Anti-STOML2 Antibody (aa161-189) - LS-C156169 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
STOML2 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The STOML2 antibody detected the STOML2 protein (arrow).

Anti-STOML2 Antibody (aa199-213) - LS-C345058 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Endogenous SLP-2 is localized to the mitochondria (Immunocytochemical staining). . Endogenous SLP-2 (green) (up) and endogenous mitochondrial HSP70 (red) (middle) were detected in methanol fixed HeLa cells using anti-SLP-2, pAb (1:100) and a pAb to mitochondrial HSP70, respectively. . Picture courtesy of Dr. Sandrine Da Cruz, University of Geneva.

Anti-STOML2 Antibody (aa173-356) - LS-C179181 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STOML2 Antibody (clone 1F5) - LS-C340461 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F5
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-STOML2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)(1:150).

SLP-2 Antibody - NBP2-38943 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLP-2 Antibody [NBP2-38943] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG.  Lane 4: Human Plasma.  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissue

SLP-2 Antibody - NBP1-79903 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLP-2 Antibody [NBP1-79903] - Human 293T, Antibody Dilution: 1.0 ug/ml STOML2 is supported by BioGPS gene expression data to be expressed in HEK293T.

SLP-2 Antibody - NB100-75482 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-SLP-2 )

SLP-2 Antibody - H00030968-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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