STOML2

Gene Symbol	STOML2
Entrez Gene	30968
Alt Symbol	HSPC108, SLP-2
Species	Human
Gene Type	protein-coding
Description	stomatin (EPB72)-like 2
Other Description	EPB72-like protein 2|paraprotein target 7|paratarg-7|stomatin-like 2|stomatin-like protein 2, mitochondrial
Swissprots	Q9P042 B4E1K7 Q9UJZ1 Q96FY2 D3DRN3 Q53G29 O60376
Accessions	AAC07983 CAG30023 CAH05402 EAW58394 EAW58395 EAW58396 Q9UJZ1 AA657517 AF161458 AAF29073 AF190167 AAF09142 AF282596 AAF91466 AK027405 BAB55091 AK130546 BAC85377 AK223102 BAD96822 AK225114 AK303883 BAG64819 AK307343 AK308552 AW273545 BC002442 AAH02442 BC003025 AAH03025 BC010152 AAH10152 BC014990 AAH14990 BQ935988 BU528995 BX400542 DQ892677 ABM83603 DQ895920 ABM86846 HY039403 HY367065 NM_001287031 NP_001273960 NM_001287032 NP_001273961 NM_001287033 NP_001273962 NM_013442 NP_038470
Function	Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation. {ECO
Subcellular Location	Mitochondrion inner membrane. Mitochondrion intermembrane space. Cell membrane; Peripheral membrane protein. Membrane raft; Peripheral membrane protein. Note=Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain. A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells. Also associates with the actin cytoskeleton and membrane rafts in activated T-cells.
Tissue Specificity	Ubiquitously expressed at low levels. Expressed in lymphoid tissues (at protein level). {ECO:0000269|PubMed:10713127, ECO:0000269|PubMed:11435687, ECO:0000269|PubMed:18641330}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

STOML2 CRISPR/Cas9 KO Plasmid (h) - sc-403638 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 HDR Plasmid (h) - sc-403638-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 Double Nickase Plasmid (h) - sc-403638-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 Double Nickase Plasmid (h2) - sc-403638-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 CRISPR Activation Plasmid (h) - sc-403638-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 CRISPR Activation Plasmid (h2) - sc-403638-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 Lentiviral Activation Particles (h) - sc-403638-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 Lentiviral Activation Particles (h2) - sc-403638-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

STOML2 siRNA (h) - sc-76593 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

STOML2 shRNA Plasmid (h) - sc-76593-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

STOML2 shRNA (h) Lentiviral Particles - sc-76593-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU145711 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20754 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20754 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00209 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr00209

STOML2 siRNA (Human) - CRH9362 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

STOML2 - MBS827739 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human STOML2 (NM_013442.1) - SHH420004 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human STOML2(NM_013442.1) - SHL044506 from Creative biogene Category siRNA Species Reactivities Human

Human STOML2 siRNA - orb269864 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

STOML2 shRNA Plasmid (Human) - CHH9362 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

STOML2 miRNA 3'UTR clone - MiUTR1H-10022 from Creative biogene Species Reactivities Human

Search more