Gene Symbol | DENR |
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Entrez Gene | 8562 |
Alt Symbol | DRP, DRP1, SMAP-3 |
Species | Human |
Gene Type | protein-coding |
Description | density-regulated protein |
Other Description | smooth muscle cell associated protein-3|smooth muscle cell-associated protein 3 |
Swissprots | O43583 Q9H3U6 Q9UKZ0 |
Accessions | EAW98338 EAW98339 EAW98340 EAW98341 EAW98342 EAW98343 O43583 AB014731 BAB20268 AF038554 AAC02985 AF103800 AAF02420 AI093093 AI093455 AK299463 BAG61429 BC000925 BC007860 AAH07860 BG705827 BI871385 BP872988 CB043904 CN300034 HQ447117 ADQ31604 NM_003677 NP_003668 |
Function | May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. {ECO:0000269|PubMed:16982740, ECO:0000269|PubMed:17878526, ECO:0000269|PubMed:20713520}. |
Tissue Specificity | Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. {ECO:0000269|PubMed:9628587}. |
Human Density Regulated Protein full length protein - ab111640 from Abcam
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DENR Partial Recombinant Protein - H00008562-Q01 from Novus Biologicals
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DENR Recombinant Protein - H00008562-P01 from Novus Biologicals
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DENR Protein - NBP1-72446 from Novus Biologicals
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Human DENR protein - orb244160 from Biorbyt
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Human DENR protein - orb168222 from Biorbyt
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DENR protein (His tag) - 80R-1960 from Fitzgerald
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DENR / DRP1 (1-198, His-tag) - AR39146PU-L from Acris Antibodies
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DENR / DRP1 (1-198, His-tag) - AR39146PU-N from Acris Antibodies
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DENR / DRP1 - H00008562-P01-10 from Acris Antibodies
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DENR / DRP1 - H00008562-P01-25 from Acris Antibodies
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DENR / DRP1 - H00008562-Q01-10 from Acris Antibodies
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DENR / DRP1 - H00008562-Q01-25 from Acris Antibodies
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DENR, 1-198aa, Human, His tag, E.coli - 01-DENR-HT from ARP American Research Products
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DENR Peptide - 7755P from ProSci
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DENR fusion protein - ag1023 from Proteintech Group
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DENR Human - PRPS-933 from NeoScientific
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Recombinant Human Density-Regulated Protein - BP002893-PRO-926 from Syd Labs
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DENR, 1-198aa, Recombinant Protein - GWB-P0834B from Genway Biotech
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Recombinant Human DENR, His-tagged - DENR-28065TH from Creative Biomart
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Recombinant Human DENR, His-tagged - DENR-28066TH from Creative Biomart
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Recombinant Human DENR, His-tagged - DENR-3643H from Creative Biomart
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DENR 1-198aa - CMB-1037 from Reagent Proteins
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Recombinant Human Density-regulated protein(DENR) - CSB-YP006724HU CSB-BP006724HU CSB-MP006724HU from Cusabio
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Recombinant human Density-regulated protein - CSB-EP006724HU from Cusabio
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