DENR

Gene Symbol DENR
Entrez Gene 8562
Alt Symbol DRP, DRP1, SMAP-3
Species Human
Gene Type protein-coding
Description density-regulated protein
Other Description smooth muscle cell associated protein-3|smooth muscle cell-associated protein 3
Swissprots O43583 Q9H3U6 Q9UKZ0
Accessions EAW98338 EAW98339 EAW98340 EAW98341 EAW98342 EAW98343 O43583 AB014731 BAB20268 AF038554 AAC02985 AF103800 AAF02420 AI093093 AI093455 AK299463 BAG61429 BC000925 BC007860 AAH07860 BG705827 BI871385 BP872988 CB043904 CN300034 HQ447117 ADQ31604 NM_003677 NP_003668
Function May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. {ECO:0000269|PubMed:16982740, ECO:0000269|PubMed:17878526, ECO:0000269|PubMed:20713520}.
Tissue Specificity Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. {ECO:0000269|PubMed:9628587}.

DENR CRISPR/Cas9 KO Plasmid (h) - sc-416677 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR HDR Plasmid (h) - sc-416677-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR Double Nickase Plasmid (h) - sc-416677-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR Double Nickase Plasmid (h2) - sc-416677-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR CRISPR Activation Plasmid (h) - sc-416677-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR CRISPR Activation Plasmid (h2) - sc-416677-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR Lentiviral Activation Particles (h) - sc-416677-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR Lentiviral Activation Particles (h2) - sc-416677-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DENR siRNA (h) - sc-95769 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DENR shRNA Plasmid (h) - sc-95769-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DENR shRNA (h) Lentiviral Particles - sc-95769-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DENR RNAi - H00008562-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: DENR RNAi [H00008562-R01V] - Analysis of DENR over-expressed 293 cell line, cotransfected with DENR Validated Chimera RNAi or non-transfected control. Blot probed with H00008562-M01. GAPDH (36.1 kDa) used as loading control.

DENR RNAi - H00008562-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU106841 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7147 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7147 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11483 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11483

DENR siRNA (Human) - CRH5630 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DENR - MBS8230439 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DENR (NM_003677.3) - SHH277125 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DENR(NM_003677.3) - SHH001523 from Creative biogene

Category siRNA
Species Reactivities Human

DENR shRNA Plasmid (Human) - CHH5630 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DENR miRNA 3'UTR clone - MiUTR1H-02776 from Creative biogene

Species Reactivities Human
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