DENR

Gene Symbol DENR
Entrez Gene 8562
Alt Symbol DRP, DRP1, SMAP-3
Species Human
Gene Type protein-coding
Description density-regulated protein
Other Description smooth muscle cell associated protein-3|smooth muscle cell-associated protein 3
Swissprots O43583 Q9H3U6 Q9UKZ0
Accessions EAW98338 EAW98339 EAW98340 EAW98341 EAW98342 EAW98343 O43583 AB014731 BAB20268 AF038554 AAC02985 AF103800 AAF02420 AI093093 AI093455 AK299463 BAG61429 BC000925 BC007860 AAH07860 BG705827 BI871385 BP872988 CB043904 CN300034 HQ447117 ADQ31604 NM_003677 NP_003668
Function May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. {ECO:0000269|PubMed:16982740, ECO:0000269|PubMed:17878526, ECO:0000269|PubMed:20713520}.
Tissue Specificity Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. {ECO:0000269|PubMed:9628587}.

DENR (N-16) - sc-323784 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DENR (N-16): sc-323784. Western blot analysis of DENR expression in K-562 (A), HEK293 (B) and MCF7 (C) whole cell lysates.

DENR (22) - sc-136254 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DENR (22): sc-136254. Western blot analysis of DENR expression in HCT-8 cell lysate.

DENR (NQ-B8) - sc-134315 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
DENR (NQ-B8): sc-134315. Western blot analysis of DENR expression in human DENR transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-Density Regulated Protein antibody - ab191700 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of rat brain tissue sections labeling Density Regulated Protein antibody using ab191700 at 20 µg/mL.

Anti-Density Regulated Protein antibody - ab56422 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56422 Density Regulated Protein antibody at 1ug/ml.

Anti-DENR / Density Regulated Antibody (aa1-82, clone 10B2711, Azide-free) - LS-C183556 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10B2711

Anti-DENR / Density Regulated Antibody (aa47-76) - LS-C203799 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DENR Antibody western blot of 293 cell line lysates (35 ug/lane). The DENR antibody detected the DENR protein (arrow).

Anti-DENR / Density Regulated Antibody (aa75-125) - LS-C289714 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DENR / Density Regulated Antibody - LS-C311083 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DENR / Density Regulated Antibody (aa1-82) - LS-C307214 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DENR / Density Regulated Antibody - LS-C155261 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded HBL435 xenograft, using DENR antibody at 1:500 dilution.

Anti-DENR / Density Regulated Antibody (aa148-198) IHC-plus™ - LS-B11665 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-DENR / Density Regulated Antibody (Internal) - LS-C336157 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of DENR in rat brain tissue with DENR antibody at 5 ug/mL.

DENR Antibody - NBP2-16148 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DENR Antibody [NBP2-16148] - Sample (50 ug of whole cell lysate) A: Mouse Heart, 12% SDS PAGE gel, diluted at 1:1000.

DENR Antibody - NBP2-13913 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DENR Antibody - NBP1-50042 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: DENR Antibody [NBP1-50042] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-DRP antibody NBP1-50041 used for IP at 6 ug/mg lysate. DRP was not efficiently immunoprecipitated by rabbit anti-DRP antibody NBP1-50042, which recognizes a downstream epitope. For blotting immunoprecipitated DRP, NBP1-50042 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

DENR Antibody (1H3) - H00008562-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3
Western Blot: DENR Antibody (1H3) [H00008562-M01] - Analysis of DENR over-expressed 293 cell line, cotransfected with DENR Validated Chimera RNAi ( Cat # H00008562-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with DENR monoclonal antibody (M01), clone 1H3 (Cat # H00008562-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

DENR Antibody - H00008562-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DENR Antibody [H00008562-D01P] - Analysis of DENR expression in transfected 293T cell line by DENR polyclonal antibody.Lane 1: DENR transfected lysate(22.10 KDa).Lane 2: Non-transfected lysate.

DENR Antibody - H00008562-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DENR Antibody [H00008562-B01] - analysis of DENR expression in transfected 293T cell line by DENR MaxPab polyclonal antibody (B01). Lane 1: DENR transfected lysate (22.10 KDa). Lane 2: Non-transfected lysate.

DENR Antibody - H00008562-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

DENR Antibody - H00008562-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DENR Antibody [H00008562-B01P] - Analysis of DENR expression in transfected 293T cell line by DENR polyclonal antibody. Lane 1: DENR transfected lysate(21.78 KDa). Lane 2: Non-transfected lysate.

Anti-DENR antibody produced in rabbit - SAB1411539 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DENR: <B>Cat. No. SAB1411539</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~22.1 kDa using DENR transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-DENR antibody produced in rabbit - HPA021783 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DENR:<B>Cat. No. HPA021783</B>: Immunohistochemical staining of human testis shows moderate cytoplasmic and nuclear positivity in cells in seminiferus ducts.

Monoclonal Anti-DENR antibody produced in mouse - WH0008562M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3
<B>Immunoblotting</B><BR/>Monoclonal Anti-DENR, <B>Cat. No. WH0008562M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~35.02 kDa using immunogen protein lysate.

Anti-DENR antibody produced in chicken - GW21250 from Sigma-Aldrich

Host Chicken
Clonality Polyclonal
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