PTBP2

Gene Symbol PTBP2
Entrez Gene 58155
Alt Symbol PTBLP, brPTB, nPTB
Species Human
Gene Type protein-coding
Description polypyrimidine tract binding protein 2
Other Description PTB-like protein|neural polypyrimidine tract binding protein|neurally-enriched homolog of PTB|polypyrimidine tract-binding protein 2
Swissprots Q969N9 Q9UKA9 Q96Q76 Q8NFB1 Q8N160 Q8NFB0 Q8N0Z1
Accessions AAD09652 EAW73005 EAW73006 EAW73007 EAW73008 EAW73009 EAW73010 Q9UKA9 AB051232 BAB71742 AB051233 BAB71743 AB209266 BAD92503 AF176085 AAF14284 AF530580 AAM94624 AF530581 AAM94625 AF530582 AAM94626 AF530583 AAM94627 AF530584 AAM94628 AF530585 AAM94629 AI052528 AI968454 AK022716 AK025333 AK092216 AK295384 BAG58340 AK299755 BAG61644 AK299897 BAG61740 AK299922 BAG61757 BC016582 AAH16582 BK000526 DAA00060 BP250235 DB473562 DQ891027 ABM81953 EU176551 ABW03352 XM_011541874 XP_011540176 XM_011541875 XP_011540177 XM_011541876 XP_011540178 XR_946720 XR_946721 XR_946722 XR_946723 NM_001300985 NP_001287914 NM_001300986 NP_001287915 NM_001300987 NP_001287916 NM_001300988 NP_001287917 NM_001300989 NP_001287918 NM_001300990 NP_001287919 NM_021190 NP_067013 NR_125356 NR_125357
Function RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. {ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:12667457}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues. {ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:12213192}.

Human PTBP2 full length protein - ab163666 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163666 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human PTBP2 protein fragment - ab163667 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163667 on a 12.5% SDS-PAGE stained with Coomassie Blue.

PTBP2 Antibody Blocking Peptide - LS-E15026 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PTBP2 Antibody Blocking Peptide - LS-E15027 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PTBP2 Antibody Blocking Peptide - LS-E26498 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human PTBP2 Protein - H00058155-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human PTBP2 Protein - H00058155-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

PTBP2 blocking peptide - GTX88919-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Rat

PTBP2 Immunizing peptide - orb50326 from Biorbyt

Category Peptide
Prices $247.00
Sizes 100 μg
Species Human, Mouse, Rat

PTBP2 Blocking Peptide - 33R-5835 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PTBP2 Blocking Peptide - 33R-1284 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PTBP2 Peptide - AC21-1335-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

PTBP2 - H00058155-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PTBP2 - H00058155-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PTBP2 - H00058155-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PTBP2 - H00058155-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PTBP2 Peptide - 46-244P from ProSci

Category Peptide

Recombinant Human Polypyrimidine tract-binding protein 2(PTBP2) - CSB-YP892133HU CSB-EP892133HU CSB-BP892133HU CSB-MP892133HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Polypyrimidine tract-binding protein 2 (PTBP2), Recombinant Protein - MBS1471333 from MyBioSource

Category Protein
Prices $1,320.00, $1,320.00, $1,540.00, $1,540.00, $2,185.00, $2,185.00, $2,650.00, $2,650.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PTBP2, Peptide - MBS426620 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat

PTBP2 Protein - NBP1-92302PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

PTBP2 Peptide, Human - M34GP12637H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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