PTBP2

Gene Symbol	PTBP2
Entrez Gene	58155
Alt Symbol	PTBLP, brPTB, nPTB
Species	Human
Gene Type	protein-coding
Description	polypyrimidine tract binding protein 2
Other Description	PTB-like protein\|neural polypyrimidine tract binding protein\|neurally-enriched homolog of PTB\|polypyrimidine tract-binding protein 2
Swissprots	Q969N9 Q9UKA9 Q96Q76 Q8NFB1 Q8N160 Q8NFB0 Q8N0Z1
Accessions	AAD09652 EAW73005 EAW73006 EAW73007 EAW73008 EAW73009 EAW73010 Q9UKA9 AB051232 BAB71742 AB051233 BAB71743 AB209266 BAD92503 AF176085 AAF14284 AF530580 AAM94624 AF530581 AAM94625 AF530582 AAM94626 AF530583 AAM94627 AF530584 AAM94628 AF530585 AAM94629 AI052528 AI968454 AK022716 AK025333 AK092216 AK295384 BAG58340 AK299755 BAG61644 AK299897 BAG61740 AK299922 BAG61757 BC016582 AAH16582 BK000526 DAA00060 BP250235 DB473562 DQ891027 ABM81953 EU176551 ABW03352 XM_011541874 XP_011540176 XM_011541875 XP_011540177 XM_011541876 XP_011540178 XR_946720 XR_946721 XR_946722 XR_946723 NM_001300985 NP_001287914 NM_001300986 NP_001287915 NM_001300987 NP_001287916 NM_001300988 NP_001287917 NM_001300989 NP_001287918 NM_001300990 NP_001287919 NM_021190 NP_067013 NR_125356 NR_125357
Function	RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. {ECO:0000269\|PubMed:11003644, ECO:0000269\|PubMed:12667457}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues. {ECO:0000269\|PubMed:11003644, ECO:0000269\|PubMed:12213192}.

PTBP-2 (A-10) - sc-376316 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

PTBP-2 (A-10): sc-376316. Western blot analysis of PTBP-2 expression in non-transfected: sc-117752 (A) and human PTBP-2 transfected: sc-176393 (B) 293T whole cell lysates.

PTBP-2 (N-14) - sc-103847 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PTBP-2 (N-14): sc-103847. Western blot analysis of PTBP-2 expression in Y79 nuclear extract.

PTBP-2 (H-40) - sc-98491 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

PTBP-2 (H-40): sc-98491. Western blot analysis of PTBP-2 expression in non-transfected: sc-117752 (A) and human PTBP-2 transfected: sc-176393 (B) 293T whole cell lysates.

PTBP-2 (T-14) - sc-103849 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PTBP-2 (YY-12) - sc-101183 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

PTBP-2 (YY-12): sc-101183. Western blot analysis of PTBP-2 expression in IMR-32 whole cell lysate.

Anti-PTBP2 antibody - ab154920 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTBP2 antibody (ab154920) at 1/1000 dilution + A549 whole cell lysate at 30 µg

Anti-PTBP2 antibody - ab57619 from Abcam

Prices	$378.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-PTBP2 antibody - ab94696 from Abcam

Prices	$376.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTBP2 antibody (ab94696) at 1 µg/ml + PANC-1 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PTBP2 antibody [EPR9890] - ab154787 from Abcam

Prices	$385.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR9890

All lanes : Anti-PTBP2 antibody [EPR9890] (ab154787) at 1/1000 dilutionLane 1 : C6 cell lysateLane 2 : Neuro-2a cell lysateLane 3 : SH-SY5Y cell lysateLane 4 : Y79 cell lysateLane 5 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PTBP2 antibody [EPR9891] - ab154853 from Abcam

Prices	$379.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR9891

All lanes : Anti-PTBP2 antibody [EPR9891] (ab154853) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Y79 cell lysateLane 3 : Neuro 2a cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PTBP2 Antibody (Internal) - LS-C55337 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-PTBP2 Antibody (aa1-533, Azide-free) - LS-C328287 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-PTBP2 Antibody (N-Terminus) - LS-C31572 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTBP2 Antibody (clone 2B11) - LS-C139297 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2B11

PTBP2 monoclonal antibody (M09), clone 2B11. Western blot of PTBP2 expression in HeLa NE.

Anti-PTBP2 Antibody (aa107-156) - LS-C110592 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

PTBP2 antibody LS-C110592 Western blot of PANC1 cell lysate.

Anti-PTBP2 Antibody - LS-C334490 from LifeSpan Bioscience

Prices	$315.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of IMR-32 cell line, using PTBP2 antibody.

PTBP2 Antibody - NBP2-19997 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: PTBP2 Antibody [NBP2-19997] - A. 30 ug H1299 whole cell lysate/extract B. 30 ug HCT116 whole cell lysate/extract 7.5 % SDS-PAGE PTBP2 antibody [C1C3] dilution: 1:1000

PTBP2 Antibody - NBP1-57401 from Novus Biologicals

Prices	$139.00, $299.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: PTBP2 Antibody [NBP1-57401] - HepG2 cell lysate, concentration 1.25ug/ml.

PTBP2 Antibody - NBP1-92302 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: PTBP2 Antibody [NBP1-92302] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

PTBP2 Antibody - H00058155-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

PTBP2 Antibody (2D10-B2) - H00058155-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2D10-B2

Western Blot: PTBP2 Antibody (2D10-B2) [H00058155-M01] - PTBP2 monoclonal antibody (M01), clone 2D10-B2 Analysis of PTBP2 expression in IMR-32.

PTBP2 Antibody (2B11) - H00058155-M09 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2B11

Western Blot: PTBP2 Antibody (2B11) [H00058155-M09] - Analysis of PTBP2 expression in Hela S3 NE (Cat # L013V3).

PTBP2 Antibody - NB100-77333 from Novus Biologicals

Prices	$229.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Rabbit Anti-PTBP2 Polyclonal Antibody - bs-11928R from Bioss

Prices	$245.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Rabbit Anti-PTBP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11928R-A350 from Bioss

Prices	$325.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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