SLC51A

Gene Symbol	SLC51A
Entrez Gene	200931
Alt Symbol	OSTA, OSTalpha
Species	Human
Gene Type	protein-coding
Description	solute carrier family 51, alpha subunit
Other Description	OST-alpha|organic solute transporter alpha|organic solute transporter subunit alpha|organic solute transporter, alpha subunit|solute carrier family 51 subunit alpha
Swissprots	Q86UW1 Q6ZMC7
Accessions	EAW53665 Q86UW1 AK172837 BAD18802 AK300996 BAG62615 AK310276 AY194243 AAP23993 BC029606 AAH29606 NM_152672 NP_689885
Function	Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. {ECO:0000269|PubMed:16317684}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B (By similarity). Mainly restricted to the lateral and basal membranes of ileal enterocytes. {ECO:0000250}.
Tissue Specificity	Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat. {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OSTA full length protein - ab165873 from Abcam Category Protein Source Wheat germ Species Human

SLC51A / OSTalpha Antibody Blocking Peptide - LS-E19142 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC51A / OSTalpha Antibody Blocking Peptide - LS-E10346 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human OSTalpha Protein - H00200931-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

OST-alpha-Antibody-C-term-Blocking-Peptide - BP9838b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

OSTalpha Blocking Peptide - 33R-5169 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

OSTA - H00200931-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

OSTalpha fusion protein - ag8226 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

OSTalpha fusion protein - ag3562 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SLC51A - SLC51A-1122H from Creative Biomart Category Protein Source Mammalian Cells Species Human

OSTalpha Protein - NBP1-87507PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SLC51A Peptide, Human - M34GP14606H from Creative Peptides Category Peptide Source Synthetic. Species Human

Organic solute transporter subunit alpha (OSTA), Recombinant Protein - MBS7025227 from MyBioSource Category Protein Prices $1,150.00, $2,135.00, $3,345.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Organic solute transporter subunit alpha (osta), Recombinant Protein - MBS7025228 from MyBioSource Category Protein Prices $1,160.00, $2,145.00, $3,355.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression

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