SLC51A

Gene Symbol SLC51A
Entrez Gene 200931
Alt Symbol OSTA, OSTalpha
Species Human
Gene Type protein-coding
Description solute carrier family 51, alpha subunit
Other Description OST-alpha|organic solute transporter alpha|organic solute transporter subunit alpha|organic solute transporter, alpha subunit|solute carrier family 51 subunit alpha
Swissprots Q86UW1 Q6ZMC7
Accessions EAW53665 Q86UW1 AK172837 BAD18802 AK300996 BAG62615 AK310276 AY194243 AAP23993 BC029606 AAH29606 NM_152672 NP_689885
Function Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. {ECO:0000269|PubMed:16317684}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B (By similarity). Mainly restricted to the lateral and basal membranes of ileal enterocytes. {ECO:0000250}.
Tissue Specificity Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat. {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}.
Top Pathways Bile secretion

OSTα CRISPR/Cas9 KO Plasmid (h) - sc-405986 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα HDR Plasmid (h) - sc-405986-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα Double Nickase Plasmid (h) - sc-405986-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα Double Nickase Plasmid (h2) - sc-405986-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα CRISPR Activation Plasmid (h) - sc-405986-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα CRISPR Activation Plasmid (h2) - sc-405986-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα Lentiviral Activation Particles (h) - sc-405986-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα Lentiviral Activation Particles (h2) - sc-405986-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OSTα siRNA (h) - sc-78006 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OSTå shRNA Plasmid (h) - sc-78006-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OSTå shRNA (h) Lentiviral Particles - sc-78006-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU002031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16178 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16178 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC51A siRNA (Human) - CRJ6269 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC51A - MBS8215737 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Osta (NM_152672.5) - SHH368840 from Creative biogene

Category siRNA
Species Reactivities Human

SLC51A shRNA Plasmid (Human) - CHJ6269 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC51A miRNA 3'UTR clone - MiUTR3H-12292 from Creative biogene

Species Reactivities Human
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