SLC51A

Gene Symbol SLC51A
Entrez Gene 200931
Alt Symbol OSTA, OSTalpha
Species Human
Gene Type protein-coding
Description solute carrier family 51, alpha subunit
Other Description OST-alpha|organic solute transporter alpha|organic solute transporter subunit alpha|organic solute transporter, alpha subunit|solute carrier family 51 subunit alpha
Swissprots Q86UW1 Q6ZMC7
Accessions EAW53665 Q86UW1 AK172837 BAD18802 AK300996 BAG62615 AK310276 AY194243 AAP23993 BC029606 AAH29606 NM_152672 NP_689885
Function Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. {ECO:0000269|PubMed:16317684}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B (By similarity). Mainly restricted to the lateral and basal membranes of ileal enterocytes. {ECO:0000250}.
Tissue Specificity Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat. {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}.
Top Pathways Bile secretion

OSTα (N-15) - sc-100078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

OSTα (T-14) - sc-100079 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-OSTA antibody - ab103442 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-OSTA antibody (ab103442) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-SLC51A / OSTalpha Antibody (aa305-335, AP) - LS-C238572 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa305-335, Biotin) - LS-C238573 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa305-335, APC) - LS-C238574 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa305-335, FITC) - LS-C238576 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa305-335, PE) - LS-C238579 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa305-335, Azide-free, HRP) - LS-C248380 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa305-335) - LS-C329934 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC51A / OSTalpha Antibody (aa179-228) - LS-C116527 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
OSTALPHA antibody LS-C116527 Western blot of COLO205 cell lysate.

Anti-SLC51A / OSTalpha Antibody (aa298-327) - LS-C163280 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of OST alpha Antibody in 293 cell line lysates (35 ug/lane). OST alpha (arrow) was detected using the purified antibody.

OSTalpha Antibody - NBP1-57085 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OSTalpha Antibody [NBP1-57085] - COLO205 cells lysate, concentration 0.2-1 ug/ml.

OSTalpha Antibody - NBP1-87507 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: OSTalpha Antibody [NBP1-87507] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Anti-OSTALPHA antibody produced in rabbit - SAB2105888 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-OSTALPHA: <B>Cat. No. SAB2105888</B>: OSTalpha in COLO205 cell lysates with OSTalpha antibody at 1.0 μg/mL.

ANTI-OST ALPHA(C-TERMINAL) antibody produced in rabbit - SAB1306154 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-OST alpha (C-term): <B>Cat. No. SAB1306154</B>: Western blot analysis of OSTalpha Antibody (C-term) in 293 cell line lysates (35 μg/lane).

OSTalpha antibody - middle region (ARP53102_P050) - ARP53102_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OST-alpha-Antibody-C-term - AP9838b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of OSTalpha Antibody (C-term) (Cat. #AP9838b) in 293 cell line lysates (35ug/lane). OST alpha (arrow) was detected using the purified Pab.

OSTalpha Antibody - C-terminal region (OAAB06438) - OAAB06438 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

OSTalpha antibody, Internal - GTX45628 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

OSTalpha antibody - 70R-4593 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

OSTA (C-term) antibody - AP53124PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of OSTA Antibody (C-term) Cat.-No AP53124PU-N in 293 cell line lysates (35ug/lane). OSTA (arrow) was detected using the purified Pab.

OSTalpha Antibody - GWB-MS907G from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-OSTalpha monoclonal antibody - DCABH-16300 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

SLC51A Polyclonal Antibody - PA5-26837 from Thermo Fisher Scientific

Prices $349.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometry analysis of 293 cells using an OST alpha polyclonal antibody (Product # PA5-26837) (right) compared to a negative control cell (left) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody
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