PLA2G4A

Gene Symbol PLA2G4A
Entrez Gene 5321
Alt Symbol PLA2G4, cPLA2-alpha
Species Human
Gene Type protein-coding
Description phospholipase A2, group IVA (cytosolic, calcium-dependent)
Other Description cPLA2|calcium-dependent phospholipid-binding protein|cytosolic phospholipase A2|lysophospholipase|phosphatidylcholine 2-acylhydrolase|phospholipase A2 group IVA
Swissprots Q29R80 B1AKG4 P47712
Accessions AAS45712 AHF45879 BAA07375 EAW91217 EAW91218 P47712 AK290336 BAF83025 AK302938 BAG64096 BC114340 AAI14341 BX118890 DA451491 M68874 AAA60105 M72393 AAB00789 XM_005245267 XP_005245324 XM_011509641 XP_011507943 XM_011509642 XP_011507944 XM_011509643 XP_011507945 XR_921838 NM_024420 NP_077734
Function Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
Subcellular Location Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion.
Tissue Specificity Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium.
Top Pathways Glutamatergic synapse, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels

cPLA 2 CRISPR/Cas9 KO Plasmid (h) - sc-400678 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 HDR Plasmid (h) - sc-400678-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 Double Nickase Plasmid (h) - sc-400678-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 Double Nickase Plasmid (h2) - sc-400678-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 CRISPR Activation Plasmid (h) - sc-400678-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 CRISPR Activation Plasmid (h2) - sc-400678-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 Lentiviral Activation Particles (h) - sc-400678-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 Lentiviral Activation Particles (h2) - sc-400678-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 siRNA (h) - sc-29280 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cPLA 2 shRNA Plasmid (h) - sc-29280-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cPLA 2 shRNA (h) Lentiviral Particles - sc-29280-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLA2G4A RNAi - H00005321-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU009531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16894 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16894 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLA2G4A siRNA (Human) - CRH3562 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

cPLA 2 CRISPR/Cas9 KO Plasmid (h2) - sc-400678-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cPLA 2 HDR Plasmid (h2) - sc-400678-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human Pla2g4a (NM_024420.2) - SHH376808 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PLA2G4A(NM_024420.2) - SHR118992 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLA2G4A siRNA - orb264064 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLA2G4A shRNA Plasmid (Human) - CHH3562 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLA2G4A miRNA 3'UTR clone - MiUTR1H-07960 from Creative biogene

Species Reactivities Human
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