Gene Symbol | EDAR |
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Entrez Gene | 10913 |
Alt Symbol | DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1 |
Species | Human |
Gene Type | protein-coding |
Description | ectodysplasin A receptor |
Other Description | EDA-A1 receptor|anhidrotic ectodysplasin receptor 1|downless homolog|downless, mouse, homolog of|ectodermal dysplasia receptor|ectodysplasin 1, anhidrotic receptor|ectodysplasin-A receptor|tumor necrosis factor receptor superfamily member EDAR |
Swissprots | Q9UNE0 B4DLC5 Q9UND9 E9PC98 B2R9H2 Q52LL5 D3DX74 |
Accessions | AAD50077 EAW53868 EAW53869 Q9UNE0 AF130988 AAD50076 AI017384 AK296936 BAG59487 AK313781 BAG36519 BC093870 AAH93870 BC093872 AAH93872 CR749352 CAH18205 EU832142 ACE87492 EU832235 ACE86805 XM_006712204 XP_006712267 XM_011510502 XP_011508804 XM_011510503 XP_011508805 XM_011510504 XP_011508806 NM_022336 NP_071731 |
Function | Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in fetal kidney, lung, skin and cultured neonatal epidermal keratinocytes. Not detected in lymphoblast and fibroblast cell lines. |
Top Pathways | Cytokine-cytokine receptor interaction |
Human EDAR full length protein - ab187467 from Abcam
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Human EDAR protein fragment - ab161196 from Abcam
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EDAR Partial Recombinant Protein - H00010913-Q01 from Novus Biologicals
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Recombinant Human EDAR Fc Chimera, CF - 157-ER-100 from R&D Systems
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Cynomolgus Anhidrotic ectodysplasin receptor 1 protein - orb138730 from Biorbyt
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Human Anhidrotic ectodysplasin receptor 1 protein - orb83887 from Biorbyt
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Cynomolgus Anhidrotic ectodysplasin receptor 1 protein - orb138731 from Biorbyt
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Human Anhidrotic ectodysplasin receptor 1 protein - orb83886 from Biorbyt
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Ectodysplasin A Receptor Blocking Peptide - 33R-6971 from Fitzgerald
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EDAR protein (His tag) - 80R-3964 from Fitzgerald
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EDAR (27-448, His-tag) - AR51649PU-N from Acris Antibodies
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EDAR (27-448, His-tag) - AR51649PU-S from Acris Antibodies
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EDAR - H00010913-H01 from Acris Antibodies
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EDAR - H00010913-Q01-10 from Acris Antibodies
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EDAR - H00010913-Q01-25 from Acris Antibodies
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EDAR fusion protein - Ag12601 from Proteintech Group
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EDAR fusion protein - Ag12888 from Proteintech Group
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Recombinant Human Ectodysplasin A Receptor, Fc Chimera - EDAR-2119H from Creative Biomart
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Recombinant Human EDAR, Fc tagged - EDAR-3135H from Creative Biomart
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Recombinant Human EDAR, His tagged - EDAR-3215H from Creative Biomart
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Recombinant Human Ectodysplasin A Receptor - EDAR-1607H from Creative Biomart
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Recombinant Human EDAR, Fc-tagged - EDAR-231H from Creative Biomart
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Recombinant Human ectodysplasin A receptor, His-tagged - EDAR-606H from Creative Biomart
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Recombinant Human EDAR, GST-tagged - EDAR-12275H from Creative Biomart
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Recombinant Human EDAR, Fc-tagged, Biotinylated - EDAR-601H from Creative Biomart
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