Gene Symbol | EDAR |
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Entrez Gene | 10913 |
Alt Symbol | DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1 |
Species | Human |
Gene Type | protein-coding |
Description | ectodysplasin A receptor |
Other Description | EDA-A1 receptor|anhidrotic ectodysplasin receptor 1|downless homolog|downless, mouse, homolog of|ectodermal dysplasia receptor|ectodysplasin 1, anhidrotic receptor|ectodysplasin-A receptor|tumor necrosis factor receptor superfamily member EDAR |
Swissprots | Q9UNE0 B4DLC5 Q9UND9 E9PC98 B2R9H2 Q52LL5 D3DX74 |
Accessions | AAD50077 EAW53868 EAW53869 Q9UNE0 AF130988 AAD50076 AI017384 AK296936 BAG59487 AK313781 BAG36519 BC093870 AAH93870 BC093872 AAH93872 CR749352 CAH18205 EU832142 ACE87492 EU832235 ACE86805 XM_006712204 XP_006712267 XM_011510502 XP_011508804 XM_011510503 XP_011508805 XM_011510504 XP_011508806 NM_022336 NP_071731 |
Function | Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in fetal kidney, lung, skin and cultured neonatal epidermal keratinocytes. Not detected in lymphoblast and fibroblast cell lines. |
Top Pathways | Cytokine-cytokine receptor interaction |
EDAR (F-5) - sc-398337 from Santa Cruz Biotechnology
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EDAR (G-1) - sc-271627 from Santa Cruz Biotechnology
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EDAR (H-300) - sc-292520 from Santa Cruz Biotechnology
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EDAR (C-20) - sc-15290 from Santa Cruz Biotechnology
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EDAR (E-19) - sc-15289 from Santa Cruz Biotechnology
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EDAR (H-7) - sc-271652 from Santa Cruz Biotechnology
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Anti-EDAR antibody - ab198168 from Abcam
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Anti-EDAR antibody - ab76399 from Abcam
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Anti-EDAR antibody - ab56803 from Abcam
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Anti-EDAR antibody [AT19E8] - ab201702 from Abcam
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Anti-EDAR antibody [EPR8020] - ab137021 from Abcam
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Anti-EDAR antibody [RM0077-8L53] - ab86051 from Abcam
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Anti-EDAR Antibody (aa64-179) - LS-C307353 from LifeSpan Bioscience
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Anti-EDAR Antibody (aa80-364) - LS-C311705 from LifeSpan Bioscience
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Anti-EDAR Antibody (aa31-245) - LS-C311671 from LifeSpan Bioscience
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Anti-EDAR Antibody (aa290-339) - LS-C81432 from LifeSpan Bioscience
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Anti-EDAR Antibody (clone 244-17) - LS-C179841 from LifeSpan Bioscience
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EDAR Antibody - AF157 from Novus Biologicals
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EDAR Antibody - NBP1-84081 from Novus Biologicals
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EDAR Antibody - NBP2-16266 from Novus Biologicals
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EDAR Antibody - NBP1-69709 from Novus Biologicals
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EDAR Antibody (Renzo-2) - NBP1-97610 from Novus Biologicals
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EDAR Antibody - H00010913-A01 from Novus Biologicals
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EDAR Antibody (3A7) - H00010913-M02A from Novus Biologicals
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EDAR Antibody (6C12) - H00010913-M01 from Novus Biologicals
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