NNT

Gene Symbol	NNT
Entrez Gene	23530
Alt Symbol	GCCD4
Species	Human
Gene Type	protein-coding
Description	nicotinamide nucleotide transhydrogenase
Other Description	NAD(P) transhydrogenase, mitochondrial|pyridine nucleotide transhydrogenase
Swissprots	Q2TB60 Q13423 Q16796 Q8N3V4
Accessions	EAW56073 EAW56074 Q13423 AK297558 BAG59951 AK299622 BAG61550 AL831822 CAD38536 AM392664 CAL37542 AM393615 CAL38491 AW771969 BC032370 AAH32370 BC064402 BC110543 AAI10544 BC110544 AAI10545 BU429380 DA521839 U40490 AAC51914 Z50101 CAA90428 XM_005248274 XP_005248331 XM_005248275 XP_005248332 XM_006714461 XP_006714524 XM_011514001 XP_011512303 XM_011514002 XP_011512304 NM_012343 NP_036475 NM_182977 NP_892022
Function	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland. {ECO:0000269|PubMed:22634753}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Tissue Specificity	Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues. {ECO:0000269|PubMed:22634753}.
Top Pathways	Nicotinate and nicotinamide metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NNT 293T Cell Transient Overexpression Lysate(Denatured) - H00023530-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

NNT 293 Cell Lysate - 401934 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

NNT 293 Cell Lysate - 403568 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

NNT Overexpression Lysate (Denatured) - H00023530-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

NNT Overexpression Lysate (Native) - NBL1-13701 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

NNT (h): 293T Lysate - sc-114805 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

NNT Over-expression Lysate Product - GWB-CB832B from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

NNT Over-expression Lysate Product - GWB-8CAB60 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

NNT Overexpression Lysate (Native) - NBP2-04791 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

NNT Overexpression Lysate (Denatured) - H00023530-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human NNT Knockdown Stable Cell Line - CSC-DC010475 from Creative biogene Category Cell Line Species Human

Search more