NNT

Gene Symbol NNT
Entrez Gene 23530
Alt Symbol GCCD4
Species Human
Gene Type protein-coding
Description nicotinamide nucleotide transhydrogenase
Other Description NAD(P) transhydrogenase, mitochondrial|pyridine nucleotide transhydrogenase
Swissprots Q2TB60 Q13423 Q16796 Q8N3V4
Accessions EAW56073 EAW56074 Q13423 AK297558 BAG59951 AK299622 BAG61550 AL831822 CAD38536 AM392664 CAL37542 AM393615 CAL38491 AW771969 BC032370 AAH32370 BC064402 BC110543 AAI10544 BC110544 AAI10545 BU429380 DA521839 U40490 AAC51914 Z50101 CAA90428 XM_005248274 XP_005248331 XM_005248275 XP_005248332 XM_006714461 XP_006714524 XM_011514001 XP_011512303 XM_011514002 XP_011512304 NM_012343 NP_036475 NM_182977 NP_892022
Function The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland. {ECO:0000269|PubMed:22634753}.
Subcellular Location Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Tissue Specificity Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues. {ECO:0000269|PubMed:22634753}.
Top Pathways Nicotinate and nicotinamide metabolism

NNT CRISPR/Cas9 KO Plasmid (h) - sc-402908 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT HDR Plasmid (h) - sc-402908-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT Double Nickase Plasmid (h) - sc-402908-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT Double Nickase Plasmid (h2) - sc-402908-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT CRISPR Activation Plasmid (h) - sc-402908-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT CRISPR Activation Plasmid (h2) - sc-402908-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT Lentiviral Activation Particles (h) - sc-402908-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT Lentiviral Activation Particles (h2) - sc-402908-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NNT siRNA (h) - sc-91738 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NNT shRNA Plasmid (h) - sc-91738-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NNT shRNA (h) Lentiviral Particles - sc-91738-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NNT RNAi - H00023530-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU083691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15387 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15387 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NNT siRNA (Human) - CRH8335 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NNT RNAi - H00023530-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NNT (NM_182977.2) - SHH353368 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NNT(NM_012343.3) - SHR014880 from Creative biogene

Category siRNA
Species Reactivities Human

Human NNT siRNA - orb268837 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NNT shRNA Plasmid (Human) - CHH8335 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NNT miRNA 3'UTR clone - MiUTR1H-06827 from Creative biogene

Species Reactivities Human

NNT miRNA 3'UTR clone - MiUTR3H-09529 from Creative biogene

Species Reactivities Human
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