CASP10

Gene Symbol	CASP10
Entrez Gene	843
Alt Symbol	ALPS2, FLICE2, MCH4
Species	Human
Gene Type	protein-coding
Description	caspase 10, apoptosis-related cysteine peptidase
Other Description	CASP-10|FADD-like ICE2|FAS-associated death domain protein interleukin-1B-converting enzyme 2|ICE-like apoptotic protease 4|apoptotic protease MCH-4|caspase 10, apoptosis-related cysteine protease|caspase-10|interleukin-1B-converting enzyme 2
Swissprots	Q8IUP5 Q99845 Q92851 Q9Y2U7 Q68HC0 Q6KF62 Q8WYQ8 Q6KF63 Q9Y2U6
Accessions	AAY24291 ABJ53426 BAB32553 BAB32554 EAW70247 EAW70248 EAW70249 EAW70250 EAW70251 Q92851 AF111344 AAD28402 AF111345 AAD28403 AI696103 AJ487678 CAD32371 AJ487679 CAD32372 AK225475 AK304859 BAG65597 AK310746 AW190618 AY690601 AAU00989 BC042844 AAH42844 BP871945 BX089180 DA456072 JF432405 ADZ15622 U60519 AAC50644 U86214 AAB46730 XM_005246907 XP_005246964 XM_005246911 XP_005246968 XM_006712796 XP_006712859 XM_011511990 XP_011510292 XR_923043 XR_923044 NM_001206524 NP_001193453 NM_001206542 NP_001193471 NM_001230 NP_001221 NM_001306083 NP_001293012 NM_032974 NP_116756 NM_032976 NP_116758 NM_032977 NP_116759
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. {ECO:0000269|PubMed:11717445}.
Tissue Specificity	Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.
Top Pathways	Apoptosis, RIG-I-like receptor signaling pathway, Tuberculosis, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Caspase-10 full length protein - ab52080 from Abcam Category Protein Prices $471.00 Sizes 100 units Source E. coli Species Human

Active human Caspase-10 full length protein - ab52081 from Abcam Category Protein Prices $471.00 Sizes 100 units Source E. coli Species Human

Caspase-10 peptide - ab41705 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human Caspase-10 peptide - ab8377 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human Caspase-10 peptide - ab101384 from Abcam Category Peptide Prices $176.00 Sizes 100 µg Species Human

Human Caspase-10 protein fragment - ab172829 from Abcam Category Protein Prices $210.00 Sizes 10 µg Source E. coli Species Human

CASP10-Antibody-Center-Blocking-Peptide - BP1326c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CASP10-Antibody-C-term-Blocking-Peptide - BP1326b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Caspase-10/a recombinant protein - GTX65045 from GeneTex Category Protein Prices $329.00 Sizes 100 unit Source E. coli Species Human

Caspase-10/a recombinant protein - GTX65046 from GeneTex Category Protein Prices $219.00 Sizes 25 unit Source E. coli Species Human

Caspase-10/b recombinant protein - GTX65507 from GeneTex Category Protein Prices $329.00 Sizes 100 unit Source E. coli Species Human

Caspase-10/b recombinant protein - GTX65508 from GeneTex Category Protein Prices $219.00 Sizes 25 unit Source E. coli Species Human

Caspase 10 peptide - GTX28377 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Recombinant Human Caspase-10 (Mch 4), CF - 834-CP-010 from R&D Systems Category Protein Source E. coli-derived, Val220-Ile479, with a C-terminal 6-His tag

Caspase-10 Inhibitor Z-AEVD-FMK - FMK009 from R&D Systems Category Peptide Prices $215.00 Sizes 1 mg

CASP10 peptide - orb217020 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Caspase 10 alpha protein - 30R-2325 from Fitzgerald Category Protein Prices $275.00, $445.00 Sizes 25 units, 100 units Source E.coli Species Human

Caspase 10 beta protein - 30R-2326 from Fitzgerald Category Protein Prices $275.00, $445.00 Sizes 25 units, 100 units Source E.coli Species Human

Caspase 10 Blocking Peptide - 33R-10749 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Caspase-10 - H00000843-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Caspase-10 - H00000843-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Caspase-10 - H00000843-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Caspase-10 - H00000843-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Caspase-10 - H00000843-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Caspase-10 - H00000843-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Search more