TNFRSF10D

Gene Symbol TNFRSF10D
Entrez Gene 8793
Alt Symbol CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Other Description TNF receptor-related receptor for TRAIL|TNF-related apoptosis-inducing ligand receptor 4|TRAIL receptor 4|TRAIL receptor with a truncated death domain|decoy receptor 2|tumor necrosis factor receptor superfamily member 10D
Swissprots Q9Y6Q4 B2R8W0 Q9UBN6
Accessions CAT16465 EAW63637 Q9UBN6 AA743393 AF021232 AAC32765 AF021233 AAC32766 AF023849 AAC52053 AF029761 AAD03477 AK313528 BAG36307 AY358285 AAQ88652 BC052270 AAH52270 BU199149 CD703247 HQ448394 ADQ32874 NM_003840 NP_003831
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
Top Pathways Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

DcR2 (D13H4) Rabbit mAb - 8049 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D13H4
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct encoding full-length human DcR2 (hDcR2; +), using DcR2 (D13H4) Rabbit mAb.

DcR2 Antibody - 4741 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa cells, mock-transfected (-) or transfected with human DcR2 (+), using DcR2 Antibody.

DcR2 (C-20) - sc-7550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DcR2 (C-20): sc-7550. Western blot analysis of human recombinant DcR2 fusion protein.

DcR2 (D-15) - sc-11638 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DcR2 (D-15): sc-11638. Western blot analysis of DcR2 expression in U-937 (A), THP-1 (B), SW480 (C) and COLO 320DM (D) whole cell lysates.

DcR2 (H-52) - sc-28985 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DcR2 (H-52): sc-28985. Western blot analysis of DcR2 expression in non-transfected: sc-117752 (A) and human DcR2 transfected: sc-371573 (B) 293T whole cell lysates.

DcR2 (E-12) - sc-26535 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DcR2 (L-20) - sc-7551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DcR2 (L-20): sc-7551. Western blot analysis of human recombinant DcR2 fusion protein.

DcR2 (A-17) - sc-26534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DcR2 (B-P30) - sc-65310 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-DcR2 antibody - ab2019 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DcR2 antibody (ab2019) at 1/1000 dilution + HeLa whole cell lysateObserved band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-DcR2 antibody - ab189600 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-DcR2 antibody (ab189600) at 1/1000 dilutionLane 1 : total cell extracts from mouse brainLane 2 : total cell extracts from Jurkat cells

Anti-DcR2 antibody - ab116450 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DcR2 antibody (ab116450) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-DcR2 antibody [B-P30] - ab59511 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-P30

Anti-DcR2 antibody [EPR3588(2)] - ab108421 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3588(2)
All lanes : Anti-DcR2 antibody [EPR3588(2)] (ab108421) at 1/1000 dilutionLane 1 : Fetal liver lysateLane 2 : Fetal kidney lysateLane 3 : Human prostate lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-TRAIL-R4 / DCR2 Antibody - LS-C318902 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.

Anti-TRAIL-R4 / DCR2 Antibody (aa252-278) - LS-C162059 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of TNFRSF10D Antibody in HL-60 cell line lysates (35 ug/lane). TNFRSF10D (arrow) was detected using the purified antibody.

Anti-TRAIL-R4 / DCR2 Antibody - LS-C334520 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human stomach cancer using TNFRSF10D antibody at dilution of 1:200 (400x lens).

Anti-TRAIL-R4 / DCR2 Antibody (Internal, clone EPR3588(2)) - LS-C137977 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3588(2)
IHC of paraffin-embedded human tonsil tissue using anti-DcR2 antibody.

Anti-TRAIL-R4 / DCR2 Antibody (N-Terminus) - LS-C18136 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAIL-R4 / DCR2 Antibody (N-Terminus) - LS-C40708 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAIL-R4 / DCR2 Antibody (clone TRAIL-R4-01, FITC) - LS-C112508 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TRAIL-R4-01

Anti-TRAIL-R4 / DCR2 Antibody (Extracellular Domain, APC) - LS-C132603 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-TRAIL-R4 / DCR2 Antibody (clone TRAIL-R4-01, PE) - LS-C112538 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TRAIL-R4-01

Anti-TRAIL-R4 / DCR2 Antibody (aa249-263) - LS-C188963 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAIL-R4 / DCR2 Antibody - LS-C212034 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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