TNFRSF10D

Gene Symbol TNFRSF10D
Entrez Gene 8793
Alt Symbol CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Other Description TNF receptor-related receptor for TRAIL|TNF-related apoptosis-inducing ligand receptor 4|TRAIL receptor 4|TRAIL receptor with a truncated death domain|decoy receptor 2|tumor necrosis factor receptor superfamily member 10D
Swissprots Q9Y6Q4 B2R8W0 Q9UBN6
Accessions CAT16465 EAW63637 Q9UBN6 AA743393 AF021232 AAC32765 AF021233 AAC32766 AF023849 AAC52053 AF029761 AAD03477 AK313528 BAG36307 AY358285 AAQ88652 BC052270 AAH52270 BU199149 CD703247 HQ448394 ADQ32874 NM_003840 NP_003831
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
Top Pathways Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

DcR2 CRISPR/Cas9 KO Plasmid (h) - sc-403389 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 HDR Plasmid (h) - sc-403389-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 Double Nickase Plasmid (h) - sc-403389-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 Double Nickase Plasmid (h2) - sc-403389-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 CRISPR Activation Plasmid (h) - sc-403389-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 CRISPR Activation Plasmid (h2) - sc-403389-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 Lentiviral Activation Particles (h) - sc-403389-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 Lentiviral Activation Particles (h2) - sc-403389-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR2 siRNA (h) - sc-35185 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DcR2 shRNA Plasmid (h) - sc-35185-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DcR2 shRNA (h) Lentiviral Particles - sc-35185-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU143961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21741 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21741 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TNFRSF10D siRNA (Human) - CRH5793 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRAIL R4/TNFRSF10D/DcR2 RNAi - H00008793-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

TNFRSF10D - MBS8232418 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF10D (NM_003840.4) - SHH431868 from Creative biogene

Category siRNA
Species Reactivities Human

TNFRSF10D shRNA Plasmid (Human) - CHH5793 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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