TNFRSF10D

Gene Symbol	TNFRSF10D
Entrez Gene	8793
Alt Symbol	CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Other Description	TNF receptor-related receptor for TRAIL|TNF-related apoptosis-inducing ligand receptor 4|TRAIL receptor 4|TRAIL receptor with a truncated death domain|decoy receptor 2|tumor necrosis factor receptor superfamily member 10D
Swissprots	Q9Y6Q4 B2R8W0 Q9UBN6
Accessions	CAT16465 EAW63637 Q9UBN6 AA743393 AF021232 AAC32765 AF021233 AAC32766 AF023849 AAC52053 AF029761 AAD03477 AK313528 BAG36307 AY358285 AAQ88652 BC052270 AAH52270 BU199149 CD703247 HQ448394 ADQ32874 NM_003840 NP_003831
Function	Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
Top Pathways	Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human DcR2 protein fragment - ab157262 from Abcam Category Protein Prices $410.00 Sizes 50 µg Source HEK 293 cells Species Human

DcR2 peptide - ab8379 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human DcR2 protein fragment - ab160191 from Abcam Category Protein Source Wheat germ Species Human

TRAIL-R4 / DCR2 Antibody Blocking Peptide - LS-E2666 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRAIL-R4 / DCR2 Antibody Blocking Peptide - LS-E29871 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TRAIL-R4 / DCR2 Antibody Blocking Peptide - LS-E10177 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRAIL R4/TNFRSF10D/DcR2 Partial Recombinant Protein - H00008793-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TRAIL R4/TNFRSF10D/DcR2 Blocking Peptide - NBP1-76985PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TNFRSF10D-Antibody-C-term-Blocking-peptide - BP13742b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNFRSF10D-Antibody-Center-Blocking-Peptide - BP9526c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DcR1 peptide - GTX26096 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

DcR2 / CD264 peptide - GTX28379 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Recombinant Human TRAIL R4/TNFRSF10D Fc Chimera, CF - 633-TR-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant human Tumor necrosis factor receptor superfamily member 10D (OPCA00741) - OPCA00741 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human TRAILR4 His tag protein - orb83614 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Species Human

Human DCR2 protein - orb245362 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Cynomolgus TRAILR4 protein - orb139801 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Cells

Human TRAILR4 Fc His tag protein - orb83145 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Species Human

CD264 / TRAILR4 - H00008793-H01 from Acris Antibodies Category Protein Prices $770.00 Sizes 25 µg Source Human HEK293T cells Species Human

CD264 / TRAILR4 - H00008793-H03 from Acris Antibodies Category Protein Prices $770.00 Sizes 25 µg Source Human HEK293T cells Species Human

CD264 / TRAILR4 - H00008793-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD264 / TRAILR4 - H00008793-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD264 / TRAILR4 Control Peptide - AP30280CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

DcR2 Peptide - 2021P from ProSci Category Peptide Species Human

CD264 Recombinant Protein - 96-751 from ProSci Category Protein Prices $425.00 Sizes 200 µg Source HEK293 cells Species Human

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