CARD11

Gene Symbol	CARD11
Entrez Gene	84433
Alt Symbol	BENTA, BIMP3, CARMA1, IMD11, PPBL
Species	Human
Gene Type	protein-coding
Description	caspase recruitment domain family, member 11
Other Description	CARD-containing MAGUK protein 1|bcl10-interacting maguk protein 3|carma 1|caspase recruitment domain-containing protein 11
Swissprots	Q2NKN7 Q548H3 A4D1Z7 Q9BXL7
Accessions	AAQ96893 EAL23962 EAW87276 EAW87277 EAW87278 EAW87279 Q9BXL7 AA194010 AA594170 AF322641 AAG53402 AF352576 AAL34460 AK074049 BAB84875 AK097139 AW139089 BC111719 AAI11720 HY086990 XM_011515585 XP_011513887 XM_011515586 XP_011513888 XM_011515587 XP_011513889 NM_032415 NP_115791
Function	Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17287217}. Membrane raft {ECO:0000269|PubMed:17287217}. Note=Colocalized with DPP4 in membrane rafts.
Tissue Specificity	Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL- 60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells. {ECO:0000269|PubMed:11278692}.
Top Pathways	T cell receptor signaling pathway, B cell receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CARD11 peptide - ab23025 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Human CARD11 protein fragment - ab164588 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

CARMA1 / CARD11 Antibody Blocking Peptide - LS-E25515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CARMA1 / CARD11 Antibody Blocking Peptide - LS-E30032 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human CARD11/CARMA1 Protein - H00084433-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CARD11/CARMA1 Blocking Peptide - NBP1-77219PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

CARD11 blocking peptide - GTX89813-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Bovine

CARD11 Peptide - AC21-0343-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CARD11 / CARMA1 - H00084433-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CARD11 / CARMA1 - H00084433-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CARD11 / CARMA1 Control Peptide - AP30186CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CARD11 Peptide - 45-360P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

CARMA1 Peptide - 3189P from ProSci Category Peptide Species Human

CARD11 fusion protein - Ag17397 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

CARD11 fusion protein - ag16468 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CARD11, His-tagged - CARD11-10718H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Caspase recruitment domain-containing protein 11(CARD11) ,partial - CSB-YP866306HU CSB-EP866306HU CSB-BP866306HU CSB-MP866306HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CARD11 / CARMA1 - TP322740 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Caspase recruitment domain-containing protein 11 (CARD11), partial, Recombinant Protein - MBS1418381 from MyBioSource Category Protein Prices $860.00, $860.00, $1,085.00, $1,085.00, $1,190.00, $1,190.00, $1,650.00, $1,650.00, $1,650.00, $2,325.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CARD11, Peptide - MBS425722 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog, Bovine

CARMA1, Peptide - MBS659869 from MyBioSource Category Peptide Prices $280.00 Sizes 50 µg

CARD11 Blocking Peptide - abx061263 from Abbexa Category Peptide Species Human, Mouse

CARD11/CARMA1 Recombinant Protein Antigen - NBP2-49067PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

CARD11-Antibody-C-term-Blocking-Peptide - BP9705b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CARD11 Peptide, Human - M34GP02366H from Creative Peptides Category Peptide Source Synthetic. Species Human

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