CARD11

Gene Symbol CARD11
Entrez Gene 84433
Alt Symbol BENTA, BIMP3, CARMA1, IMD11, PPBL
Species Human
Gene Type protein-coding
Description caspase recruitment domain family, member 11
Other Description CARD-containing MAGUK protein 1|bcl10-interacting maguk protein 3|carma 1|caspase recruitment domain-containing protein 11
Swissprots Q2NKN7 Q548H3 A4D1Z7 Q9BXL7
Accessions AAQ96893 EAL23962 EAW87276 EAW87277 EAW87278 EAW87279 Q9BXL7 AA194010 AA594170 AF322641 AAG53402 AF352576 AAL34460 AK074049 BAB84875 AK097139 AW139089 BC111719 AAI11720 HY086990 XM_011515585 XP_011513887 XM_011515586 XP_011513888 XM_011515587 XP_011513889 NM_032415 NP_115791
Function Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17287217}. Membrane raft {ECO:0000269|PubMed:17287217}. Note=Colocalized with DPP4 in membrane rafts.
Tissue Specificity Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL- 60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells. {ECO:0000269|PubMed:11278692}.
Top Pathways T cell receptor signaling pathway, B cell receptor signaling pathway

CARD 11 CRISPR/Cas9 KO Plasmid (h) - sc-402770 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 HDR Plasmid (h) - sc-402770-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 Double Nickase Plasmid (h) - sc-402770-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 Double Nickase Plasmid (h2) - sc-402770-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 CRISPR Activation Plasmid (h) - sc-402770-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 CRISPR Activation Plasmid (h2) - sc-402770-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 Lentiviral Activation Particles (h) - sc-402770-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 Lentiviral Activation Particles (h2) - sc-402770-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CARD 11 siRNA (h) - sc-41994 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CARD 11 shRNA Plasmid (h) - sc-41994-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CARD 11 shRNA (h) Lentiviral Particles - sc-41994-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU084911 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU117561 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN5362 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5362 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12170 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12170

CARD11 siRNA (Human) - CRJ3468 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CARD11/CARMA1 RNAi - H00084433-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CARD11 - MBS8240345 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CARD11 (NM_032415.4) - SHH254681 from Creative biogene

Category siRNA
Species Reactivities Human

CARD11 shRNA Plasmid (Human) - CHJ3468 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CARD11 miRNA 3'UTR clone - MiUTR3H-09048 from Creative biogene

Species Reactivities Human
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