NELFA

Gene Symbol	NELFA
Entrez Gene	7469
Alt Symbol	NELF-A, P/OKcl.15, WHSC2
Species	Human
Gene Type	protein-coding
Description	negative elongation factor complex member A
Other Description	negative elongation factor A|wolf-Hirschhorn syndrome candidate 2 protein
Swissprots	A2A2T1 Q9H3P2 O95392
Accessions	EAW82545 EAW82546 EAW82547 Q9H3P2 AB044549 BAB18651 AF101434 AAC72982 AF131751 AAD20034 AI218582 AI560345 AK001304 BAG50890 AK094040 BAG52802 AK095737 BAG53117 AK126056 BAG54283 AK222853 BAD96573 BC002764 AAH02764 DB082393 EU831413 ACE87100 EU831506 ACE86425 XM_006713916 XP_006713979 XM_011513561 XP_011511863 NM_005663 NP_005654
Function	Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:12563561, ECO:0000269|PubMed:12612062}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11150502}.
Tissue Specificity	Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:10409432, ECO:0000269|PubMed:11150502, ECO:0000269|PubMed:12612062}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WHSC2 293T Cell Transient Overexpression Lysate(Denatured) - H00007469-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

WHSC2 Overexpression Lysate (Denatured) - H00007469-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

NELF-A (h): 293T Lysate - sc-177614 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

NELF-A (h2): 293T Lysate - sc-177615 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

WHSC2 Overexpression Lysate (Native) - NBP2-07719 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WHSC2 Overexpression Lysate (Denatured) - H00007469-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human WHSC2 Knockdown Stable Cell Line - CSC-DC017494 from Creative biogene Category Cell Line Species Human

Search more