NELFA

Gene Symbol	NELFA
Entrez Gene	7469
Alt Symbol	NELF-A, P/OKcl.15, WHSC2
Species	Human
Gene Type	protein-coding
Description	negative elongation factor complex member A
Other Description	negative elongation factor A|wolf-Hirschhorn syndrome candidate 2 protein
Swissprots	A2A2T1 Q9H3P2 O95392
Accessions	EAW82545 EAW82546 EAW82547 Q9H3P2 AB044549 BAB18651 AF101434 AAC72982 AF131751 AAD20034 AI218582 AI560345 AK001304 BAG50890 AK094040 BAG52802 AK095737 BAG53117 AK126056 BAG54283 AK222853 BAD96573 BC002764 AAH02764 DB082393 EU831413 ACE87100 EU831506 ACE86425 XM_006713916 XP_006713979 XM_011513561 XP_011511863 NM_005663 NP_005654
Function	Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:12563561, ECO:0000269|PubMed:12612062}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11150502}.
Tissue Specificity	Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:10409432, ECO:0000269|PubMed:11150502, ECO:0000269|PubMed:12612062}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WHSC2 full length protein - ab116197 from Abcam Category Protein Source E. coli Species Human

NELFA / WHSC2 Antibody Blocking Peptide - LS-E3598 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NELFA / WHSC2 Antibody Blocking Peptide - LS-E22285 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WHSC2 Partial Recombinant Protein - H00007469-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

WHSC2 Recombinant Protein - H00007469-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human WHSC2 Protein - NBP1-50940 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

WHSC2-Antibody-Center-Blocking-Peptide - BP14802c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human WHSC2 protein - orb169558 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

WHSC2 protein (His tag) - 80R-1615 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

NELF-A (1-539, His-tag) - AR09796PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

NELF-A (1-539, His-tag) - AR09796PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

NELF-A - H00007469-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

NELF-A - H00007469-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NELF-A - H00007469-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

WHSC2, 1-539aa, Human, His tag, E.coli - 01-P0856 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

NELF-A fusion protein - ag0708 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

WHSC2 Human - PRPS-069 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human WHSC2 Protein - BP002090-PRO-062 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-?derived. Species Human

WHSC2 Human Protein - GWB-BSP714 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

WHSC2, 1-539aa, Recombinant Protein - GWB-P1182L from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human Wolf-Hirschhorn Syndrome Candidate 2, His-tagged - WHSC2-3397H from Creative Biomart Category Protein Source E.coli.

Recombinant Human Wolf-Hirschhorn Syndrome Candidate 2, T7-tagged - WHSC2-3015H from Creative Biomart Category Protein

Recombinant Human WHSC2, His-tagged - WHSC2-30860TH from Creative Biomart Category Protein Source E. coli Species Human

WHSC2 - NKX-023 from Reagent Proteins Category Protein Prices $364.00, $2,898.00 Sizes 20.00 µg, 1 mg Source E.coli

WHSC2 1-539aa - CMB-689 from Reagent Proteins Category Protein Prices $539.00, $1,099.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

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