MPP5

Gene Symbol	MPP5
Entrez Gene	64398
Alt Symbol	PALS1
Species	Human
Gene Type	protein-coding
Description	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
Other Description	MAGUK p55 subfamily member 5|protein associated with lin seven 1|stardust
Swissprots	Q8N7I5 Q7Z631 Q9H9Q0 Q86T98 Q8N3R9 A1L380
Accessions	CAD22414 CAD22415 EAW80930 Q8N3R9 AF131764 AI245706 AK022677 BAB14172 AK057160 AK098373 BAC05295 AK291240 BAF83929 AL832326 CAD38620 AL832578 CAD89937 AL832936 CAH56281 AM392599 CAL37477 AM392859 CAL37737 BC037966 BC053366 AAH53366 BC095485 AAH95485 BC129933 AAI29934 DA095710 DR003886 XM_005268003 XP_005268060 XM_011537086 XP_011535388 XM_011537087 XP_011535389 NM_001256550 NP_001243479 NM_022474 NP_071919
Function	May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Cell junction, tight junction. Note=Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. In the retina, detected at the outer limiting membrane (OLM), apical to the adherens junction (AJ), where it colocalizes with CRB1. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM). Localized to the Purkinje cell body and axon.
Tissue Specificity	Expressed in the retina (at protein level). {ECO:0000269|PubMed:15558731, ECO:0000269|PubMed:15914641}.
Top Pathways	Tight junction, Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MPP5 full length protein - ab132220 from Abcam Category Protein Source Wheat germ Species Human

Human MPP5 peptide - ab45562 from Abcam Category Peptide Species Human

Human MPP5 protein fragment - ab163831 from Abcam Category Protein Source Wheat germ Species Human

MPP5 Antibody Blocking Peptide - LS-E25657 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MPP5 Antibody Blocking Peptide - LS-E15790 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MPP5 Antibody Blocking Peptide - LS-E15791 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PALS1/MPP5 Protein - H00064398-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PALS1/MPP5 Protein - H00064398-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MPP5-Antibody-C-term-Blocking-Peptide - BP16584b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MPP5 blocking peptide - GTX89702-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Pig

MPP5 Blocking Peptide - 33R-5436 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MPP5 Blocking Peptide - 33R-1585 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MPP5 Peptide - AC21-0487-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MPP5 - H00064398-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MPP5 - H00064398-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MPP5 - H00064398-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MPP5 - H00064398-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MPP5 Peptide - 45-898P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

PALS1 fusion protein - Ag12010 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PALS1 fusion protein - Ag12029 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MPP5, GST-tagged - MPP5-954H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Membrane Protein, Palmitoylated 5 (MPP5) - RPA744Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Membrane Protein, Palmitoylated 5 (MPP5) - RPA744Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human MAGUK p55 subfamily member 5(MPP5) - CSB-YP847626HU CSB-EP847626HU CSB-BP847626HU CSB-MP847626HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MPP5 - TP324752 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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