RNF216

Gene Symbol RNF216
Entrez Gene 54476
Alt Symbol CAHH, TRIAD3, U7I1, UBCE7IP1, ZIN
Species Human
Gene Type protein-coding
Description ring finger protein 216
Other Description E3 ubiquitin-protein ligase RNF216|triad domain-containing protein 3|ubiquitin-conjugating enzyme 7-interacting protein 1|zinc finger protein inhibiting NF-kappa-B
Swissprots Q7Z2H7 Q6Y691 Q9NWF9 Q8NHW7 Q75ML7 Q9NYT1 Q7Z7C1
Accessions AAS07532 EAW87347 EAW87348 EAW87349 Q9NWF9 AF228527 AAF36723 AF513717 AAP47174 AF513718 AAP47175 AK000916 BAA91422 AK024787 AK092767 AK123635 BAG53927 AK128551 AK292396 BAF85085 AK297231 BAG59714 AK297416 BAG59849 AK314332 BAG36978 AM392630 CAL37508 AM393688 CAL38564 AY062174 AAL38043 AY177396 AAO60361 AY177397 AAO60362 AY177398 AAO60363 BC000787 AAH00787 BC004947 BC040728 BC063825 AAH63825 BM793093 BM970811 BM997118 BQ018569 BX537406 CAD97648 XM_005249785 XP_005249842 XM_006715748 XP_006715811 XM_011515434 XP_011513736 XM_011515435 XP_011513737 XM_011515436 XP_011513738 XR_242090 NM_207111 NP_996994 NM_207116 NP_996999 NM_019011
Function Isoform 1 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down- regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Isoform 3/ZIN inhibits TNF and IL-1 mediated activation of NF-kappa-B. Promotes TNF and RIP mediated apoptosis. {ECO:0000269|PubMed:15107846, ECO:0000269|PubMed:19893624}.
Subcellular Location Cytoplasm.
Tissue Specificity Ubiquitous, with the highest levels of expression in testis and peripheral blood leukocytes.

TRIAD3 (T-20) - sc-69056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRIAD3 (D-23) - sc-130901 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TRIAD3 (D-23): sc-130901. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplasmic localization.

Anti-TRIAD3 antibody - ab25961 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-TRIAD3 antibody (ab25961) at 0.5 µg/mlLane 2 : Anti-TRIAD3 antibody (ab25961) at 1 µg/mlLane 3 : Anti-TRIAD3 antibody (ab25961) at 2 µg/mlLane 1 : Mouse heart cell lysatesLane 2 : Mouse heart cell lysatesLane 3 : Mouse heart cell lysates

Anti-TRIAD3 antibody - ab38541 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TRIAD3 antibody (ab38541) at 1/100 dilution + Mouse kidney tissue lysate

Anti-TRIAD3 antibody - ab177520 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 Primary: Rabbit anti-TRIAD3 antibody, 1 ugSample: HeLa whole cell lysate (1 mg for IP; 20% of IP loaded) immunoprecipitated with ab177520 at 6 μg/mg lysate.Secondary: Anti-rabbit HRP conjugated antibodyLane 2 Primary: Rabbit anti-TRIAD3 antibody, 1 ugSample: HeLa whole cell lysate (1 mg for IP; 20% of IP loaded) immunoprecipitated with control IgG at 6 μg/mg lysate.Secondary: Anti-rabbit HRP conjugated antibody

Anti-TRIAD3 antibody - N-terminal - ab189113 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-TRIAD3 antibody - N-terminal (ab189113) at 0.5 µg/mlLane 2 : Anti-TRIAD3 antibody - N-terminal (ab189113) at 1 µg/mlLane 3 : Anti-TRIAD3 antibody - N-terminal (ab189113) at 2 µg/mlLane 1 : mouse heart cell lysateLane 2 : mouse heart cell lysateLane 3 : mouse heart cell lysate

Anti-RNF216 / TRIAD3 Antibody (aa350-400) IHC-plus™ - LS-B2090 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RNF216 / TRIAD3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2090 concentration 5 ug/ml.

Anti-RNF216 / TRIAD3 Antibody (N-Terminus) IHC-plus™ - LS-B1430 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RNF216 / TRIAD3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1430 concentration 5 ug/ml.

Anti-RNF216 / TRIAD3 Antibody (C-Terminus, Biotin) - LS-C246209 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (C-Terminus, FITC) - LS-C246211 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (C-Terminus, AP) - LS-C246208 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (C-Terminus, APC) - LS-C246210 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (C-Terminus, PE) - LS-C246216 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (C-Terminus, Azide-free, HRP) - LS-C247938 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (aa775-825) - LS-C286242 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (aa1-50) - LS-C290756 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (aa816-866) - LS-C290759 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (C-Terminus) - LS-C330709 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF216 / TRIAD3 Antibody (aa101-150) - LS-C187213 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Mouse Thymus. Rnf216 antibody dilution 1.0 ug/ml.

Anti-RNF216 / TRIAD3 Antibody - LS-C26906 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 g/ml

Anti-RNF216 / TRIAD3 Antibody (aa100-150) - LS-C290757 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse RNF216 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, and mouse TCMK-1 cells. Antibodies: Affinity purified rabbit anti-RNF216 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-RNF216 / TRIAD3 Antibody (aa716-745) - LS-C98008 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

TRIAD3A Antibody - NB100-56891 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TRIAD3A Antibody - NBP1-76592 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TRIAD3A Antibody [NBP1-76592] - Analysis of TRIAD3A in mouse heart tissue lysate with TRIAD3A antibody at (A) 1 and (B) 2 ug/mL.

TRIAD3 Antibody - NBP1-86907 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more