EBI3

Gene Symbol	EBI3
Entrez Gene	10148
Alt Symbol	IL-27B, IL27B
Species	Human
Gene Type	protein-coding
Description	Epstein-Barr virus induced 3
Other Description	EBV-induced gene 3 protein|Epstein-Barr virus induced gene 3|IL-27 subunit beta|IL27 subunit|IL35 subunit|cytokine receptor|epstein-Barr virus-induced gene 3 protein|interleukin-27 subunit beta
Swissprots	O75269 A0N0N2 Q14213
Accessions	AAC33488 ABK41923 CBX32665 CBX32666 EAW69244 EAW69245 Q14213 BC015364 AAH15364 BC046112 AAH46112 DQ891589 ABM82515 EU176581 ABW03382 L08187 AAA93193 XM_011527619 XP_011525921 NM_005755 NP_005746
Function	Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T- helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. {ECO:0000269|PubMed:12121660}.
Subcellular Location	Secreted.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse EBI3 / IL-27B ELISA Kit (Sandwich ELISA) - LS-F7281 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 0.156-10 ng/ml

Mouse EBI3 / IL-27B ELISA Kit (Sandwich ELISA) - LS-F11771 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 0.156-10 ng/ml

Human EBI3 / IL-27B ELISA Kit (Sandwich ELISA) - LS-F11772 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 0.156-10 ng/ml

Interleukin-27 subunit beta (EBI3), Human, ELISA Kit - CSB-EL007360HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin-27 subunit beta, EBI3, Human, ELISA Kit - E9188h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 31.2-2000 pg/mL

Epstein Barr Virus Induced Protein 3 (EBI3), Human, CLIA Kit - SCD206Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 0.103ng/mL Range 0.312-20ng/mL

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS2602012 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5 pg/ml Range 1000 pg/ml-15.6pg/ml

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS2602581 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS269916 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.05 ng/ml. Range 10 ng/ml-0.156 ng/ml

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS2600810 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS2601594 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS2601903 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

epstein-barr virus IgM, EBv IgM, ELISA Kit - MBS9302546 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Epstein-Barr virus induced 3, ELISA Kit - MBS924266 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human EBI3 is typically less than 3.9 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 15.6 pg/ml -1000 pg/ml.

IL-35, ELISA Kit - MBS2506294 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

IL-35, ELISA Kit - MBS2511987 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

IL-35, ELISA Kit - MBS2504842 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

IL-35, ELISA Kit - MBS2504651 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

interleukin 27 EBI3 (IL-27 EBI3), ELISA Kit - MBS2600181 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) - SCD206Hu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 1.12pg/mL. Range 2.74-2000pg/mL The standard curve concentrations used for the CLIA’s were 2000pg/mL, 666.67pg/mL, 222.22pg/mL, 74.07pg/mL, 24.69pg/mL, 8.23pg/mL, 2.74pg/mL

ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) - SED206Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) - SCD206Mu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 5.79pg/mL. Range 13.72-10000pg/mL The standard curve concentrations used for the CLIA’s were 10000pg/mL, 3333.33pg/mL, 1111.11pg/mL, 370.37pg/mL, 123.46pg/mL, 41.15pg/mL, 13.72pg/mL

Human IL-27 Platinum ELISA - BMS2085* from eBioscience Prices $429.00, $2,889.00 Sizes 96 tests, 10 x 96 tests Sensitivity 9.5 pg/mL Range 62.5 - 4,000 pg/mL

Human Interleukin-27 subunit beta(EBI3) ELISA kit - CSB-EL007360HU from Cusabio Category ELISA Kit Sensitivity 3.9 pg/ml. Range 15.6 pg/ml-1000 pg/ml

CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) - SCD206Hu from Cloud-clone Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 1.12pg/mL. Range 2.743-2000pg/mL The standard curve concentrations used for the ELISA's were 2000pg/mL, 666.67pg/mL, 222.22pg/mL, 74.07pg/mL, 24.691pg/mL, 8.23pg/mL, 2.743pg/mL

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