EBI3

Gene Symbol	EBI3
Entrez Gene	10148
Alt Symbol	IL-27B, IL27B
Species	Human
Gene Type	protein-coding
Description	Epstein-Barr virus induced 3
Other Description	EBV-induced gene 3 protein|Epstein-Barr virus induced gene 3|IL-27 subunit beta|IL27 subunit|IL35 subunit|cytokine receptor|epstein-Barr virus-induced gene 3 protein|interleukin-27 subunit beta
Swissprots	O75269 A0N0N2 Q14213
Accessions	AAC33488 ABK41923 CBX32665 CBX32666 EAW69244 EAW69245 Q14213 BC015364 AAH15364 BC046112 AAH46112 DQ891589 ABM82515 EU176581 ABW03382 L08187 AAA93193 XM_011527619 XP_011525921 NM_005755 NP_005746
Function	Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T- helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. {ECO:0000269|PubMed:12121660}.
Subcellular Location	Secreted.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EBI3 Gene - orb90693 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-EBI3-cDNA-Clone - DC04066 from Abgent, a WuXi AppTec company Prices $309.15 Sizes 10 µg Species Human Accession BC015364

EBI3 - MBS1269899 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC015364

Human EBI3 cDNA clone(NM_005755.2) - CDFH005595 from Creative Biomart Species Human Accession NM_005755.2

Human EBI3 ORF Clone(NM_005755.2) - CDCR291245 from Creative Biomart Species Human Accession NM_005755.2

Human EBI3 ORF Clone(NM_005755.2) - CDCR291246 from Creative Biomart Species Human Accession NM_005755.2

Human EBI3 ORF Clone(NM_005755.2) - CDCR291247 from Creative Biomart Species Human Accession NM_005755.2

Human EBI3 / IL27b Gene ORF cDNA clone in cloning vector - HG10117-M from Sino Biological Species Human

Human EBI3 / IL27b Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10117-M-F from Sino Biological Species Human Accession NM_005755.2

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid - HG10117-M-N from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, N-His tag - HG10117-NH from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid - HG10117-UT from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, C-HA tag - HG10117-CY from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, C-His tag - HG10117-CH from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10117-NF from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10117-CF from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, N-HA tag - HG10117-NY from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10117-NM from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10117-ACG from Sino Biological Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10117-CM from Sino Biological Species Human

Human IL27b ORF clone(NM_005755.2) - CDCL184867 from Creative biogene Species Human

Human EBI3 ORF Clone (BC015364) - CDCS412409 from Creative biogene Species Human Accession Q14213

Human EBI3 cDNA Clone(NM_005755.2) - CDFH005595 from Creative biogene Species Human

Human EBI3 / IL27b Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10117-ACR from Sino Biological Species Human

Cyno Monkey IL-27/IL-35 EBI3 (XP_005587614) VersaClone cDNA - RDC2083 from R&D Systems Prices $199.00 Sizes 10 µg Species Monkey

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