EBI3

Gene Symbol	EBI3
Entrez Gene	10148
Alt Symbol	IL-27B, IL27B
Species	Human
Gene Type	protein-coding
Description	Epstein-Barr virus induced 3
Other Description	EBV-induced gene 3 protein|Epstein-Barr virus induced gene 3|IL-27 subunit beta|IL27 subunit|IL35 subunit|cytokine receptor|epstein-Barr virus-induced gene 3 protein|interleukin-27 subunit beta
Swissprots	O75269 A0N0N2 Q14213
Accessions	AAC33488 ABK41923 CBX32665 CBX32666 EAW69244 EAW69245 Q14213 BC015364 AAH15364 BC046112 AAH46112 DQ891589 ABM82515 EU176581 ABW03382 L08187 AAA93193 XM_011527619 XP_011525921 NM_005755 NP_005746
Function	Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T- helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. {ECO:0000269|PubMed:12121660}.
Subcellular Location	Secreted.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active mouse EBI3 protein fragment - ab125813 from Abcam Category Protein Source E. coli Species Mouse

Human EBI3 full length protein - ab83026 from Abcam Category Protein Source E. coli Species Human

Human EBI3 full length protein - ab123759 from Abcam Category Protein Source E. coli Species Human

Human EBI3 full length protein - ab166879 from Abcam Category Protein Source E. coli Species Human

Human EBI3 full length protein - ab82903 from Abcam Category Protein Source E. coli Species Human

Human EBI3 full length protein - ab187217 from Abcam Category Protein Source E. coli Species Human

EBI3 / IL-27B Antibody Blocking Peptide - LS-E26908 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EBI3 / IL-27B Antibody Blocking Peptide - LS-E30631 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EBI3 / IL-27B Antibody Blocking Peptide - LS-E30635 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EBI3 / IL-27B Antibody Blocking Peptide - LS-E15549 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IL-27/IL-35 EBI3 Subunit Protein - H00010148-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human IL-27/IL-35 EBI3 Subunit Protein - H00010148-P01 from Novus Biologicals Category Protein Prices $319.00, $529.00 Sizes 2 µg, 25 µg Source Wheat Germ Species Human

IL-27/IL-35 EBI3 Subunit Blocking Peptide - NBP1-76976PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

IL-27/IL-35 EBI3 Subunit Blocking Peptide - NBP1-76980PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human IL-27/IL-35 EBI3 Subunit Protein - NBP1-99326 from Novus Biologicals Category Protein Prices $185.00 Sizes 20 µg Source E. coli Species Human

IL-27/IL-35 EBI3 Subunit Protein - NBP1-99763 from Novus Biologicals Category Protein Species Human

IL-27/IL-35 EBI3 Subunit Recombinant Protein - P4568 from Novus Biologicals Category Protein Prices $549.00 Sizes 20 µg Species Human

EBI3 blocking peptide - GTX88539-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human IL-35 Fc Chimera, CF - 8608-IL-050 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived

EBI3 Protein (OPPA02008) - OPPA02008 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

EBI3 Protein (OPPA02439) - OPPA02439 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human EBI3 protein - orb139189 from Biorbyt Category Protein Prices $221.00, $400.00, $612.00 Sizes 5 μg, 10 μg, 20 μg Source CHO Stable Cells Species Human

Human EBI3 protein - orb80295 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Mouse EBI3 protein - orb80297 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Mouse

EBI3 Blocking Peptide - 33R-8990 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Search more