BAD

Gene Symbol	BAD
Entrez Gene	572
Alt Symbol	BBC2, BCL2L8
Species	Human
Gene Type	protein-coding
Description	BCL2-associated agonist of cell death
Other Description	BCL-X/BCL-2 binding protein|BCL2-antagonist of cell death protein|BCL2-binding component 6|BCL2-binding protein|bcl-2-binding component 6|bcl-2-like protein 8|bcl-XL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-L-8|bcl2-associated agonist of cell death
Swissprots	O14803 Q6FH21 Q92934
Accessions	EAW74233 EAW74234 EAW74235 EAW74236 Q92934 AB451254 BAG70068 AB451378 BAG70192 AF021792 AAB72092 AF031523 AAB88124 AK023420 AK291863 BAF84552 AK303051 BAG64171 AK309150 AW014069 BC001901 AAH01901 BC095431 AAH95431 BE255791 BG435829 BG748336 BT006678 AAP35324 CR541935 CAG46733 CR541959 CAG46757 DQ895784 ABM86710 EU176363 ABW03814 U66879 AAB36516 NM_004322 NP_004313 NM_032989 NP_116784
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. {ECO:0000250}.
Subcellular Location	Mitochondrion outer membrane. Cytoplasm {ECO:0000250|UniProtKB:Q61337}. Note=Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. {ECO:0000250|UniProtKB:Q61337}.
Tissue Specificity	Expressed in a wide variety of tissues.
Top Pathways	Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BAD-Over-expression-Lysate - LY12202a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

BAD 293 Cell Lysate - 402790 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Bad Overexpression Lysate (Native) - NBP2-07881 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Bad Overexpression Lysate (Native) - NBL1-07900 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Bad (h): 293T Lysate - sc-111517 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Bad (h3): 293T Lysate - sc-170552 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

BAD Over-expression Lysate Product - GWB-4C8E93 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Bad Overexpression Lysate (Native) - NBP2-09800 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Bad Overexpression Lysate (Denatured) - H00000572-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Bad Overexpression Lysate (Denatured) - H00000572-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

BAD-knockout Cell lysate - LC810019 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human BAD Knockdown Stable Cell Line - CSC-DC001295 from Creative biogene Category Cell Line Species Human

Human BAD Knockout Cell Line-HeLa - CSC-RT0633 from Creative biogene Category Cell Line Species Human

BAD KO Cell Lysate-HeLa - CLKO-0139 from Creative biogene Category Cell Lysate

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