BAD

Gene Symbol	BAD
Entrez Gene	572
Alt Symbol	BBC2, BCL2L8
Species	Human
Gene Type	protein-coding
Description	BCL2-associated agonist of cell death
Other Description	BCL-X/BCL-2 binding protein|BCL2-antagonist of cell death protein|BCL2-binding component 6|BCL2-binding protein|bcl-2-binding component 6|bcl-2-like protein 8|bcl-XL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-L-8|bcl2-associated agonist of cell death
Swissprots	O14803 Q6FH21 Q92934
Accessions	EAW74233 EAW74234 EAW74235 EAW74236 Q92934 AB451254 BAG70068 AB451378 BAG70192 AF021792 AAB72092 AF031523 AAB88124 AK023420 AK291863 BAF84552 AK303051 BAG64171 AK309150 AW014069 BC001901 AAH01901 BC095431 AAH95431 BE255791 BG435829 BG748336 BT006678 AAP35324 CR541935 CAG46733 CR541959 CAG46757 DQ895784 ABM86710 EU176363 ABW03814 U66879 AAB36516 NM_004322 NP_004313 NM_032989 NP_116784
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. {ECO:0000250}.
Subcellular Location	Mitochondrion outer membrane. Cytoplasm {ECO:0000250|UniProtKB:Q61337}. Note=Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. {ECO:0000250|UniProtKB:Q61337}.
Tissue Specificity	Expressed in a wide variety of tissues.
Top Pathways	Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Bad peptide - ab7985 from Abcam Category Peptide

Bad peptide - ab171725 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Bad full length protein - ab89848 from Abcam Category Protein Prices $235.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Mouse Bad full length protein - ab58730 from Abcam Category Protein Source E. coli Species Mouse

BAD Antibody Blocking Peptide - LS-E2287 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E2225 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E10548 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E10562 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E30076 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

BAD Antibody Blocking Peptide - LS-E7491 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7490 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7492 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7493 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7494 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7495 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7496 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7497 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7498 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7500 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7499 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7501 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7503 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7502 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7245 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAD Antibody Blocking Peptide - LS-E7246 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

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